Functional Analysis of the Ferric Uptake Regulator Gene fur in Xanthomonas vesicatoria

文献类型： 外文期刊

第一作者： Liu, Huiqin

作者： Liu, Huiqin;Dong, Chunling;Zhao, Tingchang;Wang, Tieling;Liu, Huiqin;Han, Jucai;Wen, Xiangzhen;Huang, Qi

作者机构：

期刊名称：PLOS ONE （ 影响因子：3.24； 五年影响因子：3.788 ）

ISSN： 1932-6203

年卷期： 2016 年 11 卷 2 期

页码：

收录情况： SCI

摘要： Iron is essential for the growth and survival of many organisms. Intracellular iron homeostasis must be maintained for cell survival and protection against iron toxicity. The ferric uptake regulator protein (Fur) regulates the high-affinity ferric uptake system in many bacteria. To investigate the function of the fur gene in Xanthomonas vesicatoria (Xv), we generated a fur mutant strain, fur-m, by site-directed mutagenesis. Whereas siderophore production increased in the Xv fur mutant, extracellular polysaccharide production, biofilm formation, swimming ability and quorum sensing signals were all significantly decreased. The fur mutant also had significantly reduced virulence in tomato leaves. The above-mentioned phenotypes significantly recovered when the Xv fur mutation allele was complemented with a wild-type fur gene. Thus, Fur either negatively or positively regulates multiple important physiological functions in Xv.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序