Alternariol 9-methyl ether from the endophytic fungus Alternaria sp Samif01 and its bioactivities
文献类型: 外文期刊
第一作者: Lou, Jingfeng
作者: Lou, Jingfeng;Yu, Ruiting;Wang, Xiaohan;Mao, Ziling;Fu, Linyun;Zhou, Ligang;Liu, Yang
作者机构:
关键词: Salvia miltiorrhiza Bunge;Endophytic fungus;Alternaria sp., Alternariol 9-methyl ether;Bioactivity
期刊名称:BRAZILIAN JOURNAL OF MICROBIOLOGY ( 影响因子:2.476; 五年影响因子:3.391 )
ISSN: 1517-8382
年卷期: 2016 年 47 卷 1 期
页码:
收录情况: SCI
摘要: One bioactive compound, identified as alternariol 9-methyl ether, was isolated from the crude extract of the endophytic fungus Alternaria sp. Samif01 residing in the roots of Salvia miltiorrhiza Bunge. Alternariol 9-methyl ether was active against bacteria with minimum inhibitory concentration values ranging from 25 to 75mug/mL and median inhibitory concentration (IC50) values ranging from 16.00 to 38.27 mu g/mL. The IC50 value of alternariol 9-methyl ether against spore germination of Magnaporthe oryzae was 87.18 mu g/mL. Alternariol 9-methyl ether also showed antinematodal activity against Bursaphelenchus xylophilus and Caenorhabditis elegans with IC50 values of 98.17 mu g/mL and 74.62 mu g/mL, respectively. This work is the first report on alternariol 9-methyl ether and its biological activities from the endophytic fungus Alternaria sp. Samif01 derived from S. miltiorrhiza Bunge. The results indicate the potential of Alternaria sp. Samif01 as a source of alternariol 9-methyl ether and also support that alternariol 9-methyl ether is a natural compound with high potential bioactivity against microorganisms. (C) 2015 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda.
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