Population Variation Reveals Independent Selection toward Small Body Size in Chinese Debao Pony

文献类型： 外文期刊

第一作者： Kader, Adiljan

作者： Kader, Adiljan;Dong, Kunzhe;Zhao, Qianjun;He, Xiaohong;Pu, Yabin;Gorkhali, Neena Amatya;Liu, Xuexue;Jiang, Lin;Li, Xiangchen;Guan, Weijun;Ma, Yuehui;Li, Yan;Zhang, Yaping;Wu, Dong-Dong;Irwin, David M.;Liu, Jianfeng

作者机构：

关键词： selective signature;di;XP-EHH;genetic differentiation;association;TBX3

期刊名称：GENOME BIOLOGY AND EVOLUTION （ 影响因子：3.416； 五年影响因子：4.079 ）

ISSN： 1759-6653

年卷期： 2016 年 8 卷 1 期

页码：

收录情况： SCI

摘要： Body size, one of the most important quantitative traits under evolutionary scrutiny, varies considerably among species and among populations within species. Revealing the genetic basis underlying this variation is very important, particularly in humans where there is a close relationship with diseases and in domestic animals as the selective patterns are associated with improvements in production traits. The Debao pony is a horse breed with small body size that is unique to China; however, it is unknown whether the size-related candidate genes identified in Western breeds also account for the small body size of the Debao pony. Here, we compared individual horses from the Debao population with other two C hinese horse populations using single nucleotide polymorphisms (5NPs) identified with the Equine SNP 65 Bead Chip. The previously reported size-related candidate gene HMGA2 showed a significant signature for selection, consistent with its role observed in human populations. More interestingly, we found a candidate gene TBX3, which had not been observed in previous studies on horse body size that displayed the highest differentiation and most significant association, and thus likely is the dominating factor for the small stature of the Debao pony. Further comparison between the Debao pony and other breeds of horses from around the world demonstrated that TBX3 was selected independently in the Debao pony, suggesting that there were multiple origins of small stature in the horse.

分类号：

  • 相关文献

[1]Identifying Genetic Differences Between Dongxiang Blue-Shelled and White Leghorn Chickens Using Sequencing Data. Zhao, Qing-bo,Sun, Hao,Zhang, Zhe,Wang, Qi-shan,Zhang, Xiang-zhe,Pan, Yu-chun,Liao, Rong-rong,Yang, Chang-suo,Wang, Qi-shan,Zhang, Xiang-zhe,Pan, Yu-chun. 2018

[2]A push-pull strategy to control aphids combines intercropping with semiochemical releases. Hatt, Severin,Zhang, Yong,Chen, Julian,Xu, Qinxuan,Hatt, Severin,Lopes, Thomas,Zhang, Yong,Francis, Frederic,Hatt, Severin,Bodson, Bernard. 2018

[3]Genome-wide CNV analysis reveals variants associated with growth traits in Bos indicus. Zhou, Yang,Xu, Lingyang,Hay, El Hamidi Abdel,Bickhart, Derek M.,Rosen, Benjamin D.,Schroeder, Steven G.,Sonstegard, Tad S.,Van Tassell, Curtis P.,Liu, George E.,Zhou, Yang,Utsunomiya, Yuri T.,Garcia, Jose Fernando,Xu, Lingyang,Alexandre, Pamela Almeida,Sterman Ferraz, Jose Bento,Fukumasu, Heidge,de Rezende Neves, Haroldo Henrique,Garcia, Jose Fernando,Sonstegard, Tad S.,Garcia, Jose Fernando. 2016

[4]Determination of Residual Feed Intake and Its Associations with Single Nucleotide Polymorphism in Chickens. Xu Zhen-qiang,Chen Jie,Zhang De-xiang,Zhang Xi-quan,Zhang Yan,Ji Cong-liang. 2014

[5]Associations of GBP2 gene copy number variations with growth traits and transcriptional expression in Chinese cattle. Zhang, Gui-Min,He, Hua,Song, Cheng-Chuang,Cao, Xiu-Kai,Lei, Chu-Zhao,Lan, Xian-Yong,Chen, Hong,Huang, Yong-Zhen,Zheng, Li,He, Hua,Zhang, Zi-Jing,Qi, Xing-Lei. 2018

[6]Copy number variations at LEPR gene locus associated with gene expression and phenotypic traits in Chinese cattle. Shi, Tao,Xu, Yao,Yang, Mingjuan,Huang, Yongzhen,Lan, Xianyong,Lei, Chuzhao,Chen, Hong,Yang, Xiaoming,Qi, Xinglei.

[7]Identification and characterization of a novel adenine phosphoribosyltransferase gene (ZmAPT2) from maize (Zea mays L.). Wu, Suowei,Yu, Zhanwang,Li, Weihua,Yang, Qingkai,Ye, Chunjiang,Sun, Yan,Jin, Demin,Wang, Bin,Wu, Suowei,Li, Weihua,Yang, Qingkai,Wang, Fengge,Zhao, Jiuran.

[8]TaCKX6-D1, the ortholog of rice OsCKX2, is associated with grain weight in hexaploid wheat. Zhang, Lei,Zhao, Yong-Liang,Gao, Li-Feng,Zhao, Guang-Yao,Zhou, Rong-Hua,Jia, Ji-Zeng,Zhang, Lei,Zhang, Bao-Shi.

[9]DNA methylation pattern of Photoperiod-B1 is associated with photoperiod insensitivity in wheat (Triticum aestivum). Sun, Han,Guo, Zhiai,Gao, Lifeng,Zhao, Guangyao,Zhang, Wenping,Zhou, Ronghua,Wu, Yongzhen,Jia, Jizeng,Sun, Han,An, Hailong,Wang, Haiyang.

[10]Subcellular localization, expression patterns, SNPs and association analyses of the porcine HUMMLC2B gene. Wang, Huan L.,Wang, Heng,Zhu, Zheng M.,Wang, Chen F.,Zhu, Meng J.,Mo, De L.,Yang, Shu L.,Li, Kui.

[11]Polymorphisms in GJA1 and their association with growth traits in chicken. Shahjahan, M.,Liu, R. R.,Zhao, G. P.,Zhang, J. J.,Zheng, M. Q.,Li, Q. H.,Wen, J.,Liu, R. R.,Zhao, G. P.,Zhang, J. J.,Zheng, M. Q.,Li, Q. H.,Wen, J.. 2015

[12]Association of polygalacturonase-inhibiting protein gene 2 (MsPGIP2) to common leaf spot resistance in alfalfa. Gui, Zhi,Gao, Jianming,Xin, Nan,Pi, Yongshuo,Liu, Huiqin,Gui, Zhi,Gao, Jianming,Wang, Yu,Yuan, Qinghua,Li, Xianglin.

[13]Novel Nucleotide Variations, Haplotypes Structure and Associations with Growth Related Traits of Goat AT Motif-Binding Factor (ATBF1) Gene. Zhang, Xiaoyan,Wu, Xianfeng,Pan, Chuanying,Lei, Chuzhao,Chen, Hong,Lan, Xianyong,Jia, Wenchao,Li, Xiangcheng.

[14]Association of Calpain 1 (CAPN1) and HRSP12 allelic variants in beef cattle with carcass traits. Hou, Guanyu,Huang, Meng,Gao, Xue,Li, Junya,Gao, Huijiang,Ren, Hongyan,Xu, Shangzhong,Hou, Guanyu. 2011

[15]Characterization and identification of ISSR markers associated with oil content in sea buckthorn berries. Ding, J.,Bao, Y. H.,Ding, J.,Ruan, C. J.,Li, H.,Ding, J.,Guan, Y.,Shan, J. Y.. 2016

[16]SNP and haplotype analysis of paired box 3 (PAX3) gene provide evidence for association with growth traits in Chinese cattle. Xu, Yao,Cai, Hanfang,Zhou, Yang,Shi, Tao,Lan, Xianyong,Lei, Chuzhao,Chen, Hong,Zhang, Chunlei,Jia, Yutang.

[17]Genetic Variants in SDC3 Gene are Significantly Associated with Growth Traits in Two Chinese Beef Cattle Breeds. Huang, Yong-Zhen,Wang, Qin,Zhang, Chun-Lei,Fang, Xing-Tang,Chen, Hong,Huang, Yong-Zhen,Song, En-Liang.

[18]Association analysis of bovine Foxa2 gene single sequence variant and haplotype combinations with growth traits in Chinese cattle. Liu, Mei,Li, Mijie,Wang, Shaoqiang,Xu, Yao,Lan, Xianyong,Li, Zhuanjian,Lei, Chuzhao,Chen, Hong,Yang, Dongying,Jia, Yutang,Li, Mijie,Li, Mijie.

[19]Association of the circadian rhythmic expression of GmCRY1a with a latitudinal cline in photoperiodic flowering of soybean. Zhang, Qingzhu,Li, Hongyu,Li, Rui,Hu, Ruibo,Fan, Chengming,Chen, Fulu,Liu, Xu,Fu, Yongfu,Lin, Chentao,Zhang, Qingzhu,Wang, Zonghua,Lin, Chentao.

[20]Genetic differentiation of Bemisia tabaci (Gennadius) (Hemiptera : Aleyrodidae) biotype Q based on mitochondrial DNA markers. Chu, Dong,Tao, Yun-Li,Liu, Guo-Xia,Fan, Zhong-Xue,Bi, Yu-Ping,Wan, Fang-Hao. 2008

作者其他论文 更多>>

微信小程序