Pan-genome bridges wheat structural variations with habitat and breeding

文献类型： 外文期刊

第一作者： Jiao, Chengzhi

作者： Jiao, Chengzhi;Hao, Chenyang;Xie, Yuxin;Zhao, Li;Li, Tian;Fu, Junjie;Hou, Jian;Liu, Hongxia;Liu, Xu;Jia, Jizeng;Mao, Long;Zhang, Xueyong;Jiao, Chengzhi;Wang, Xiue;Xie, Xiaoming;Wang, Zihao;Zhang, Yuqi;Guo, Weilong;Chen, Liyang;Garg, Vanika;Chitikineni, Annapurna;Appels, Rudi;Varshney, Rajeev K.;Dwivedi, Girish;Dwivedi, Girish;Appels, Rudi

作者机构：

期刊名称：NATURE （ 影响因子：48.5； 五年影响因子：55.0 ）

ISSN： 0028-0836

年卷期： 2025 年 637 卷 8045 期

页码：

收录情况： SCI

摘要： Wheat is the second largest food crop with a very good breeding system and pedigree record in China. Investigating the genomic footprints of wheat cultivars will unveil potential avenues for future breeding efforts(1,2). Here we report chromosome-level genome assemblies of 17 wheat cultivars that chronicle the breeding history of China. Comparative genomic analysis uncovered a wealth of structural rearrangements, identifying 249,976 structural variations with 49.03% (122,567) longer than 5 kb. Cultivars developed in 1980s displayed significant accumulations of structural variations, a pattern linked to the extensive incorporation of European and American varieties into breeding programmes of that era. We further proved that structural variations in the centromere-proximal regions are associated with a reduction of crossover events. We showed that common wheat evolved from spring to winter types via mutations and duplications of the VRN-A1 gene as an adaptation strategy to a changing environment. We confirmed shifts in wheat cultivars linked to dietary preferences, migration and cultural integration in Northwest China. We identified large presence or absence variations of pSc200 tandem repeats on the 1RS terminal, suggesting its own rapid evolution in the wheat genome. The high-quality genome assemblies of 17 representatives developed and their good complementarity to the 10+ pan-genomes offer a robust platform for future genomics-assisted breeding in wheat.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序