Analysis of Small Molecule Compounds by Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry with ZnO, CuO and NiO Nanoparticles as Matrix

文献类型： 外文期刊

第一作者： Yang Meng-Rui

作者： Yang Meng-Rui;Wang Min;Tang Xiao-Yan;Zhou Jian;Mao Xue-Fei

作者机构：

关键词： Nanoparticles;Matrix-assisted laser desorption ionization time-of-flight mass spectrometry;Organic small molecule compounds

期刊名称：CHINESE JOURNAL OF ANALYTICAL CHEMISTRY （ 影响因子：1.134； 五年影响因子：0.909 ）

ISSN： 0253-3820

年卷期： 2015 年 43 卷 7 期

页码：

收录情况： SCI

摘要： Transition metal oxide ZnO nanoparticles as inorganic matrix was adopted in the matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) analysis of small molecule compounds including sugars and stearic acid and its performances were investigated. In addition, the feasibility of metal ion selective ionization of L-arginine by using NiO and CuO nanoparticles as matrix directly was explored initially. In the experiment, the analyte and nanoparticle suspension were mixed on the sample plate. The crystal of analyte and matrix was excited by 337 nm laser after the solvent was evaporated, and then detected under reflection mode of TOF-MS. The results indicated that ZnO nanoparticles with high UV absorption could eliminate the interference of conventional matrix, simplify the mass spectra, and enhance the peak intensity of stearic acid under negative mode. Moreover, Cu+ ion selective ionization of L-arginine was achieved in comparison of CuO and NiO as matrix for MALDI-TOF-MS analysis of L-arginine.

分类号：

  • 相关文献

[1]Preparation and characterization of alpha-galactosidase-loaded chitosan nanoparticles for use in foods. Liu, Yong,Li, Yanli,Xu, Shaochun,Tang, Jiangwu,Xu, Yaoxing,Sun, Yan,Ding, Juntao. 2011

[2]Characteration of Protein Loaded Chitosan Nanoparticles at Different pH Values. Liu, Yong,Li, Yanli,Xu, Shaochun,Xu, Yaoxing,Sun, Yan. 2011

[3]Development of Ligand Incorporated Chitosan Nanoparticles for the Selective Delivery of 5-Fluorouracil to Colon. Li, Puwang,She, F. H.,Kong, L. X.,Li, Puwang,Li, Puwang,Peng, Zheng. 2011

[4]Green synthesis of gold nanoparticles using Citrus maxima peel extract and their catalytic/antibacterial activities. Yuan, Chun-Gang,Huo, Can,Gui, Bing,Cao, Wei-Ping. 2017

[5]Fast and selective recognizes polysaccharide by surface molecularly imprinted film coated onto aldehyde-modified magnetic nanoparticles. Huang, Weiwei,Yang, Xin,Zhao, Song,Zhang, Min,Hu, Xinglong,Wang, Jing,Zhao, Haitian,Huang, Weiwei,Yang, Xin,Zhang, Min,Wang, Jing,Huang, Weiwei.

[6]Chitosan-Modified PLGA Nanoparticles with Versatile Surface for Improved Drug Delivery. Wang, Yichao,Li, Puwang,Kong, Lingxue,Li, Puwang. 2013

[7]Utilization of Chitosan-Lactide Copolymer Nanoparticles as Controlled Release Pesticide Carrier for Pyraclostrobin Against Colletotrichum gossypii Southw. Huang, Qi-Liang,Xu, Lei,Cao, Li-Dong,Li, Feng-Min,Wang, Xiang-Jing.

[8]Impact of Metal and Metal Oxide Nanoparticles on Plant: A Critical Review. Rastogi, Anshu,Rastogi, Anshu,Zivcak, Marek,Sytar, Oksana,Brestic, Marian,Sytar, Oksana,Kalaji, Hazem M.,Kalaji, Hazem M.,He, Xiaolan,Mbarki, Sonia. 2017

[9]Formulation Optimization For High Drug Loading Colonic Drug Delivery Carrier. Wang, Yichao,Li, Puwang,Kong, Lingxue,Peng, Zheng,Luo, Yongyue. 2010

[10]Tangeretin-loaded protein nanoparticles fabricated from zein/beta-lactoglobulin: Preparation, characterization, and functional performance. Chen, Jingjing,Zheng, Jinkai,McClements, David Julian,Xiao, Hang,Zheng, Jinkai. 2014

[11]The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review. Cao, Yi,Gong, Yu,Zhou, Yiwei,Fang, Xin,Zhang, Cao,Li, Yining,Li, Juan,Cao, Yi,Liu, Liangliang,Zhou, Yiwei,Fang, Xin. 2017

[12]Epigallocatechin gallate-beta-lactoglobulin nanoparticles improve the antitumor activity of EGCG for inducing cancer cell apoptosis. Wu, Min,Jin, Peng,Qin, Dingkui,Wang, Kai,Du, Qizhen,Jin, Jianchang,Xu, Yongquan,Yin, Junfeng. 2017

[13]Construction of novel amphiphilic chitosan copolymer nanoparticles for chlorpyrifos delivery. Zhang, Jiakun,Li, Min,Huang, Qiliang,Fan, Tengfei,Xu, Qing,Wu, Yan,Chen, Chunying.

[14]Interactions Analysis in BSA-loaded Chitosan Nanoparticles at Different pH Values. Liu, Yong,Li, Yanli,Xu, Shaochun,Xu, Yaoxing,Sun, Yan. 2011

[15]Enhanced Germicidal Efficacy by Co-Delivery of Validamycin and Hexaconazole with Methoxy Poly(ethylene glycol)-Poly(lactide-co-glycolide) Nanoparticles. Zhang, Jiakun,Zhao, Caiyan,Wu, Yan,Zhang, Jiakun,Liu, Yajing,Cao, Lidong,Huang, Qiliang.

[16]Improving the Effectiveness of (-)-Epigallocatechin Gallate (EGCG) against Rabbit Atherosclerosis by EGCG-Loaded Nanoparticles Prepared from Chitosan and Polyaspartic Acid. Hong, Zhiyong,Jin, Jianchang,Du, Qizhen,Xu, Yongquan,Yin, Jun-Feng,Jiang, Yongwen,Xu, Yongquan,Yin, Jun-Feng,Jiang, Yongwen.

[17]Induction of mucosal immune responses and protection of cattle against direct-contact challenge by intranasal delivery with foot-and-mouth disease virus antigen mediated by nanoparticles. Pan, Li,Zhang, Zhongwang,Lv, Jianliang,Zhou, Peng,Hu, Wenfa,Fang, Yuzhen,Chen, Haotai,Liu, Xinsheng,Shao, Junjun,Zhao, Furong,Ding, Yaozhong,Lin, Tong,Chang, Huiyun,Zhang, Jie,Zhang, Yongguang,Wang, Yonglu,Zhang, Zhongwang,Lv, Jianliang,Zhou, Peng,Hu, Wenfa,Fang, Yuzhen,Chen, Haotai,Liu, Xinsheng,Shao, Junjun,Zhao, Furong,Ding, Yaozhong,Lin, Tong,Chang, Huiyun,Zhang, Jie,Zhang, Yongguang,Wang, Yonglu. 2014

[18]Desulfurization and bio-regeneration of adsorbents with magnetic P-delafieldii R-8 cells. Li, Wangliang,Xing, Jianmin,Li, Yuguang,Xiong, Xiaochao,Liu, Huizhou,Li, Wangliang,Li, Yuguang,Xiong, Xiaochao,Li, Xin. 2008

[19]In situ SERS detection of emulsifiers at lipid interfaces using label-free amphiphilic gold nanoparticles. Li, Yue,Driver, Michael,Winuprasith, Thunnalin,Zheng, Jinkai,McClements, David Julian,He, Lili,Li, Yue,Winuprasith, Thunnalin,Zheng, Jinkai.

[20]A SIMPLE ROUTE TO CONTROLLABLY SYNTHESIZE WATER-SOLUBLE ZNCDTE NANORODS AND NANOPARTICLES. Wang Yan,Cui Hai-Xin,Sun Chang-Jiao,Hou Yan-Bing,Lu Yun-Zhang. 2011

作者其他论文 更多>>

微信小程序