文献类型： 外文期刊
第一作者： Xing, Linlin
作者： Xing, Linlin;Yu, Hui;Qi, Jingjing;Jiang, Pan;Sun, Bingqing;Cui, Junsheng;Ou, Changcan;Hu, Qinghai;Xing, Linlin;Chang, Weishan
作者机构：
期刊名称：PLOS ONE （ 影响因子：3.24； 五年影响因子：3.788 ）
ISSN： 1932-6203
年卷期： 2015 年 10 卷 6 期
页码：
收录情况： SCI
摘要： To investigate the genetic basis of erythromycin resistance in Riemerella anatipestifer, the MIC to erythromycin of 79 R. anatipestifer isolates from China and one typed strain, ATCC11845, were evaluated. The results showed that 43 of 80 (53.8%) of the tested R. anatipestifer strains showed resistance to erythromycin, and 30 of 43 erythromycin-resistant R. anatipestifer strains carried ermF or ermFU with an MIC in the range of 32-2048 mu g/ml, while the other 13 strains carrying the ereD gene exhibited an MIC of 4-16 mu g/ml. Of 30 ermF + R. anatipestifer strains, 27 (90.0%) carried the ermFU gene which may have been derived from the CTnDOT-like element, while three other strains carried ermF from transposon Tn4351. Moreover, sequence analysis revealed that ermF, ermFU, and ereD were located within the multiresistance region of the R. anatipestifer genome.
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