Correlation analysis between single nucleotide polymorphism of DRD1 gene and stereotyped behavior of blue fox

文献类型： 外文期刊

第一作者： Liu, Z. Y.

作者： Liu, Z. Y.;Ren, E. J.;Ba, H. X.;Wu, Q.;Zhu, H. W.;Xing, X. M.;Yang, F. H.

作者机构：

关键词： Blue fox;Stereotyped behavior;SNP;DRD1 gene

期刊名称：GENETICS AND MOLECULAR RESEARCH （ 影响因子：0.764； 五年影响因子：0.912 ）

ISSN： 1676-5680

年卷期： 2015 年 14 卷 2 期

页码：

收录情况： SCI

摘要： This study was performed to investigate the correlation between stereotyped behavior of the blue fox and single nucleotide polymorphisms (SNPs) of the DRD1 gene. We choose the DRD1 gene as a major gene for investigating the correlation of gene polymorphism and self-biting disease by means of direct sequencing. Part of the DRD1 gene exon of the blue fox was cloned; the length of the whole sequence was 864 bp. Four SNPs were detected and analyzed by the chi-square analysis; the results showed that the gene polymorphism of T206C in the DRD1 gene had a significant correlation with self-biting (P < 0.01). Therefore, marker-assistant selection on self-biting of blue foxes using these SNPs can be applied to select healthy individuals.

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