Tissue deposition and residue depletion in rainbow trout following continuous voluntary feeding with various levels of melamine or a blend of melamine and cyanuric acid

文献类型： 外文期刊

第一作者： Liu, Haiyan

作者： Liu, Haiyan;Xue, Min;Wang, Jia;Wu, Xiufeng;Zheng, Yinhua;Li, Junguo;Qin, Yuchang;Liu, Haiyan;Xue, Min;Qiu, Jing;Qin, Yuchang

作者机构：

关键词： Melamine;Cyanuric acid;Deposition;Depletion;Rainbow trout;Continuous voluntary feeding

期刊名称：COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY （ 影响因子：3.228； 五年影响因子：3.289 ）

ISSN： 1532-0456

年卷期： 2014 年 166 卷

页码：

收录情况： SCI

摘要： This study determined the deposition and depletion in rainbow trout after continuous administration of melamine (MEL) alone or a blend of MEL and cyanuric acid (CYA). The plasma, muscles, kidneys, liver and gills were sampled at 0, 3, 7, 13, 21, 28 and 42d. After the final sampling at 42d, fish from the MEL0.05, MEL20 and MCA groups were fed the control diet (MEL0) for the depletion test. Co-administration with cyanuric add accelerated the deposition time to the Css for melamine: during the withdrawal phrase, the melamine and CYA concentrations in the tissues decreased exponentially. Compared to the t(1/2) for single oral administration, the t(1/2) for melamine and cyanuric acid after 42d continuous feeding was prolonged. The presence of trace CYA in the plasma and kidneys of trout was detected in the MEL20 group, indicating that MEL can convert into CYA in rainbow trout. (C) 2014 Elsevier Inc. All rights reserved.

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