Biological detoxification of zearalenone by Aspergillus niger strain FS10

文献类型： 外文期刊

第一作者： Sun, Xiulan

作者： Sun, Xiulan;He, Xingxing;Li, Yun;Qian, He;Li, Yun;Xu, Dan;Xue, Kathy Siyu

作者机构：

关键词： Zearalenone;Biodetoxification;Aspergillus niger FS10;Corn steep liquor

期刊名称：FOOD AND CHEMICAL TOXICOLOGY （ 影响因子：6.023； 五年影响因子：5.844 ）

ISSN： 0278-6915

年卷期： 2014 年 72 卷

页码：

收录情况： SCI

摘要： Zearalenone (ZEN) contamination of corn and cereal products is a serious health hazard throughout the world and its elimination by microbial methods is now being widely examined. In this study, an Aspergillus niger strain, FS10, isolated from Chinese fermented soybean, was shown to reduce levels of ZEN in corn steep liquor (CSL). Spores, mycelium and culture filtrate of the strain FS10 were tested for their ability to remove ZEN. The results indicated that strain FS10 could remove 89.56% of ZEN from potato dextrose broth (PDB) medium. Mycelium and culture filtrate decreased the ZEN content by 43.10% and 68.16%, respectively. The contaminated corn steep liquor initially contained ZEN 29 mu g/ml, 60.01% of which could be removed by strain FS10. To demonstrate the loss of toxicity in vivo, the culture filtrate incubated with the contaminated corn steep liquor for 48 h was administered to rats. The results indicated that the contaminated corn steep liquor severely damaged liver and kidney tissue. Rats administered with contaminated corn steep liquor treated with the strain FS10 culture filtrate showed significantly less severe liver and kidney damage, and organ index values were comparable to the non-ZEN-exposed control (p < 0.05). Our study suggests an effective approach to reduce the hazards of ZEN in corn steep liquor. (C) 2014 Elsevier Ltd. All rights reserved.

分类号：

  • 相关文献

[1]Cloning, expression of a peroxiredoxin gene from Acinetobacter sp SM04 and characterization of its recombinant protein for zearalenone detoxification. Yu, Yuanshan,Wu, Hui,Yu, Yuanshan,Wu, Hui,Tang, Yuqian,Qiu, Liping. 2012

[2]The Mycotoxin Zearalenone Hinders Candida albicans Biofilm Formation and Hyphal Morphogenesis. Rajasekharan, Satish Kumar,Lee, Jin-Hyung,Lee, Jintae,Zhao, Yueju. 2018

[3]Rapid detection and quantification of zearalenone-producing Fusarium species by targeting the zearalenone synthase gene PKS4. Meng, Kun,Wang, Yaru,Yang, Peilong,Luo, Huiying,Bai, Yingguo,Shi, Pengjun,Yuan, Tiezheng,Ma, Rui,Yao, Bin. 2010

[4]Secretory expression and characterization of a novel peroxiredoxin for zearalenone detoxification in Saccharomyces cerevisiae. Wu, Hui,Yu, Yuanshan. 2013

[5]The Antagonistic Effect of Mycotoxins Deoxynivalenol and Zearalenone on Metabolic Profiling in Serum and Liver of Mice. Ji, Jian,Cui, Fangchao,Pi, Fuwei,Zhang, Yinzhi,Li, Yun,Wang, Jiasheng,Sun, Xiulan,Zhu, Pei,Ji, Jian,Zhu, Pei,Cui, Fangchao,Pi, Fuwei,Zhang, Yinzhi,Sun, Xiulan,Li, Yun,Wang, Jiasheng. 2017

[6]Screening and monitoring zearalenone-producing Fusarium species by PCR and zearalenone by monoclonal antibodies in feed from China. Pei, Shi-Chun,Zhang, Hong-Fu,Ji, Cheng,Pei, Shi-Chun,Zhen, Yu-Ping,Gao, Jian-Wei,Lee, Won-Jong,Chen, Cong,Zhang, Xuan-Zhe.

[7]Iron (II, III) oxide/multi-walled carbon nanotube composite as solid-phase extraction sorbent followed by ultra-high performance liquid chromatography tandem mass spectrometry for simultaneous determination of zearalenone and type A trichothecenes in Salviae miltiorrhizae Radix et Rhizoma (Danshen). Jiang, Keqiu,Huang, Peng,Luan, Lianjun,Wu, Yongjiang,Fan, Kai,Guo, Wenbo,Zhao, Zhihui,Han, Zheng.

[8]Recent mycotoxin survey data and advanced mycotoxin detection techniques reported from China: a review. Selvaraj, Jonathan Nimal,Wang, Yan,Zhou, Lu,Zhao, Yueju,Xing, Fuguo,Dai, Xiaofeng,Liu, Yang.

[9]A novel detoxifying agent: Using rice husk carriers to immobilize zearalenone-degrading enzyme from Aspergillus niger FS10. He, Mengling,Li, Yun,Pi, Fuwei,Ji, Jian,He, Xingxing,Zhang, Yinzhi,Sun, Xiulan,Li, Yun.

[10]Individual and combined cytotoxicity assessment of zearalenone with ochratoxin A or alpha-zearalenol by full factorial design. Zheng, N.,Gao, Y. N.,Wang, H. W.,Wang, J. Q.,Zheng, N.,Gao, Y. N.,Wang, J. Q.,Wang, H. W.,Liu, J.. 2018

[11]Mycotoxin detection - Recent trends at global level. Selvaraj, Jonathan Nimal,Zhou Lu,Wang Yan,Zhao Yue-ju,Xing Fu-guo,Dai Xiao-feng,Liu Yang. 2015

[12]Rapid and sensitive quantitation of zearalenone in food and feed by lateral flow immunoassay. Liu, Gang,Han, Zheng,Nie, Dongxia,Yang, Junhua,Zhao, Zhihui,Song, Suquan,Wu, Aibo,Liu, Gang,Zhang, Jingbo,Li, Heping,Liao, Yucai,Song, Suquan,De Saeger, Sarah. 2012

[13]Metabolic Profile of Zearalenone in Liver Microsomes from Different Species and Its in Vivo Metabolism in Rats and Chickens Using Ultra High-Pressure Liquid Chromatography-Quadrupole/Time-of-Flight Mass Spectrometry. Yang, Shupeng,Zhang, Jinzhen,Jin, Yue,Zhou, Jinhui,Li, Yi,Yang, Shupeng,Zhang, Huiyan,De Ruyck, Karl,De Saeger, Sarah,De Boevre, Marthe,Yang, Shupeng,Zhang, Huiyan,Sun, Feifei,Wang, Zhanhui,Zhang, Suxia,Li, Yanshen. 2017

[14]Effects of aflatoxin B1 combined with ochratoxin A and/or zearalenone on metabolism, immune function, and antioxidant status in lactating dairy goats. Huang, Shuai,Fan, Caiyun,Wang, Shang,Cheng, Jianbo,Zheng, Nan,Jabar, Adil,Wang, Jiaqi,Cheng, Ming. 2018

[15]Multi-component immunochromatographic assay for simultaneous detection of aflatoxin B-1, ochratoxin A and zearalenone in agro-food. Li, Xin,Li, Peiwu,Zhang, Qi,Li, Ran,Zhang, Wen,Zhang, Zhaowei,Ding, Xiaoxia,Tang, Xiaoqian,Li, Xin,Zhang, Qi,Li, Ran,Zhang, Zhaowei,Li, Xin,Li, Peiwu,Li, Peiwu,Zhang, Zhaowei,Ding, Xiaoxia,Li, Peiwu,Zhang, Qi,Li, Ran,Zhang, Wen,Tang, Xiaoqian. 2013

[16]Evaluation of reduced toxicity of zearalenone as measured by the Hep G2 cell assay on degradation enzymes. He, Xingxing,Li, Yun,Gu, Wenshu,Sun, Yange,Sun, Xiulan,Li, Shuai,Li, Yun.

[17]Occurrence of mycotoxins in feed ingredients and complete feeds obtained from the Beijing region of China. Zhao, Lihong,Fan, Yu,Ma, Shanshan,Ji, Cheng,Ma, Qiugang,Zhang, Jianyun,Jia, Yaxiong,Sun, Lei.

[18]Cytotoxicity induced by ochratoxin A, zearalenone, and alpha-zearalenol: Effects of individual and combined treatment. Wang, H. W.,Wang, J. Q.,Li, S. L.,Zhang, Y. D.,Zheng, N.,Wang, H. W.,Li, F. D.,Wang, H. W.,Wang, J. Q.,Li, S. L.,Zhang, Y. D.,Zheng, N.,Zheng, B. Q.. 2014

[19]Optimization for the Production of Deoxynivalenol and Zearalenone by Fusarium graminearum Using Response Surface Methodology. Wu, Li,Qiu, Lijuan,Zhang, Huijie,Sun, Juan,Hu, Xuexu,Wang, Bujun,Wu, Li,Zhang, Huijie,Sun, Juan,Hu, Xuexu,Wang, Bujun. 2017

[20]Occurrence of four mycotoxins in cereal and oil products in Yangtze Delta region of China and their food safety risks. Li, Rui,Wang, Xu,Zhou, Yu,Zhou, Ting,Yang, Dongxu,Wang, Qi. 2014

作者其他论文 更多>>

微信小程序