Involvement of Arabidopsis Histone Acetyltransferase HAC Family Genes in the Ethylene Signaling Pathway

文献类型： 外文期刊

第一作者： Xu, Jiang

作者： Xu, Jiang;Li, Chao;Xu, Jiang;Li, Jian;Li, Qingyun;Yang, Hongchun;Li, Chao

作者机构：

关键词： HAC family genes;Histone acetyltransferase

期刊名称：PLANT AND CELL PHYSIOLOGY （ 影响因子：4.927； 五年影响因子：5.516 ）

ISSN： 0032-0781

年卷期： 2014 年 55 卷 2 期

页码：

收录情况： SCI

摘要： Epigenetic modifications play a fundamental role in regulating chromatin dynamics and gene expression. The level of histone acetylation is controlled by two functionally antagonistic enzymes, namely histone acetyltransferase (HAT) and histone deacetylase (HDAC). CREB-binding protein (CBP)/p300 proteins, a subfamily of highly conserved HATs, are involved in various physiological events including proliferation, differentiation and apoptosis. In this work, we study the poorly known function of their homologous genes, the HAC genes, in Arabidopsis. We found that hac1-involved mutants displayed pleiotropic phenotypes, in particular hypersensitivity to ethylene both in the dark and in the light. We also found that the transcriptional levels of ethylene-responsive genes are significantly higher in the hac1hac5 double mutant than in wild-type plants. Moreover, an ethylene synthesis inhibitor cannot release the triple responses of hac mutants. These results suggest that HACs are involved in the ethylene signaling pathway.

分类号：

  • 相关文献

[1]The histone acetyltransferase PsGcn5 mediates oxidative stress responses and is required for full virulence of Phytophthora sojae. Zhao, Wei,Wang, Tao,Liu, Shusen,Chen, Qingqing,Qi, Rende,Zhao, Wei,Wang, Tao,Qi, Rende.

作者其他论文 更多>>

微信小程序