RPS8-a New Informative DNA Marker for Phylogeny of Babesia and Theileria Parasites in China
文献类型： 外文期刊
第一作者： Tian, Zhan-Cheng
作者： Tian, Zhan-Cheng;Liu, Guang-Yuan;Yin, Hong;Luo, Jian-Xun;Guan, Gui-Quan;Luo, Jin;Xie, Jun-Ren;Shen, Hui;Tian, Mei-Yuan;Zheng, Jin-feng;Yuan, Xiao-song;Wang, Fang-fang
作者机构：
期刊名称：PLOS ONE （ 影响因子：3.24； 五年影响因子：3.788 ）
ISSN： 1932-6203
年卷期： 2013 年 8 卷 11 期
页码：
收录情况： SCI
摘要： Piroplasmosis is a serious debilitating and sometimes fatal disease. Phylogenetic relationships within piroplasmida are complex and remain unclear. We compared the intron-exon structure and DNA sequences of the RPS8 gene from Babesia and Theileria spp. isolates in China. Similar to 18S rDNA, the 40S ribosomal protein S8 gene, RPS8, including both coding and non-coding regions is a useful and novel genetic marker for defining species boundaries and for inferring phylogenies because it tends to have little intra-specific variation but considerable inter-specific difference. However, more samples are needed to verify the usefulness of the RPS8 (coding and non-coding regions) gene as a marker for the phylogenetic position and detection of most Babesia and Theileria species, particularly for some closely related species.
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