Determination of Trace Atrazine and Two Kinds of Its Metabolites in Milk by Solid Phase Extraction and Liquid Chromatography/Mass Spectrometry

文献类型： 外文期刊

第一作者： Shi Dong-Dong

作者： Shi Dong-Dong;Liu Qing-Sheng;Shi Bo;Chang Bi-Ying

作者机构：

关键词： Liquid chromatography-tandem mass spectrometry;Milk;Atrazine;Metabolites

期刊名称：CHINESE JOURNAL OF ANALYTICAL CHEMISTRY （ 影响因子：1.134； 五年影响因子：0.909 ）

ISSN： 0253-3820

年卷期： 2013 年 41 卷 1 期

页码：

收录情况： SCI

摘要： A sensitive LC-MS method was developed for the determination of atrazine and its metabolites in cattle milk. The method can be applied to the simultaneous determination of atrazine and its major dealkylation and hydroxylation metabolites which include atrazine, hydroxyatrazine, diaminochloroatrazine, desisopropylatrazine, desethylatrazine, deethylhydroxyatrazine, deisopropylhydroxyatrazine. The analytical scheme including sample preparation, chromatographic and mass spectrometric conditions was developed and optimized. Hydrochloric acid and sodium thiosulphate were added to the sample before extracted by ice acetonitrile. The mixed cation-exchange column was found to be satisfactory for the purification of sample. High-performance liquid chromatography/mass spectrometric methods were used for the quantitative analysis of samples. The relative standard deviations for the analytes were from 1.53% to 9.04% at 1, 5, 10 and 25 mu g/L level, the recoveries range was from 62.0% to 119.0% at 1, 5, 10 and 25 mu g/L level, and the limits of detection (LOD) were from 0.1 to 0.5 mu g/L. The linear ranges of the method were from 0.4 to 100 mu g/L with R-2 values of greater than 0.99. The method is rapid, cost-effective and could be applied to assess the safety of milk exposure to atrazine related chemicals.

分类号：

  • 相关文献

[1]Determination of Amicarbazone and Its Metabolites in Corn and Its Plant with a Modified QuEChERS by Liquid Chromatography-Tandem Mass Spectrometry. Dong Mao-Feng,Bai Bing,Tang Hong-Xia,Wang Wei-Min,Zhao Zhi-Hui,Han Zheng,Song Wei-Guo. 2015

[2]Determination of 23 Perfluorinated Alkyl Substances in Fishery Products by Ultra Fast Liquid Chromatography-Tandem Mass Spectrometry. Guo Meng-Meng,Wu Hai-Yan,Li Zhao-Xin,Tan Zhi-Jun,Zhai Yu-Xiu,Guo Meng-Meng,Wu Hai-Yan,Li Zhao-Xin,Tan Zhi-Jun,Zhai Yu-Xiu. 2013

[3]Determination of Cyromazine and Melamine Residues in Vegetables by Triple Quadurupole Liquid Chromatography-Tandem Mass Spectrometry with Hydrophilic Interaction Chromatography. Qian Ming-Rong,Zhang Hu,He Hong-Mei,Wang Xiang-Yun,Chen Zhi-Min,Wu Li-Qin. 2009

[4]Simultaneous Determination of Seven Mental Drugs in Feeds by Liquid Chromatography-Tandem Mass Spectrometry. Suo De-Cheng,Zhao Gen-Long,Li Lan,Su Xiao-Ou. 2010

[5]Simultaneous Detection of 21 Kinds of Mycotoxins and Their Metabolites in Animal Plasma with Impurity Adsorption Purification Followed by Liquid Chromatography-Tandem Mass Spectrometry. Wang Rui-Guo,Su Xiao-Ou,Wang Pei-Long,Zhang Wei,Xue Yan,Li Yu. 2017

[6]Determination of Five Lipophilic Marine Toxins in Shellfish by Liquid Chromatography with Tandem Mass Spectrometry. Yao Jian-Hua,Tan Zhi-Jun,Zhou De-Qing,Yao Jian-Hua. 2010

[7]Determination of Mesotrione and Its Metabolite Residues in Maize by Ultra Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry. Deng Li-Gang,Lu Fu-Sui,Deng Li-Gang,Li Zeng-Mei,Zhao Shan-Cang,Chen Ye-Bing,Guo Chang-Ying,Deng Li-Gang,Li Zeng-Mei,Zhao Shan-Cang,Chen Ye-Bing,Guo Chang-Ying. 2013

[8]Proteomics Analysis of Porcine Serum Proteins by LC-MS/MS after Foot-and-Mouth Disease Virus (FMDV) Infection. Liu, Yongjie,Zhang, Keshan,Zheng, Haixue,Shang, Youjun,Guo, Jianhong,Tian, Hong,Lu, Guodong,Jin, Ye,He, Jijun,Cai, Xuepeng,Li, Xiangtao.

[9]Simultaneous determination of 13 phytohormones in oilseed rape tissues by liquid chromatography-electrospray tandem mass spectrometry and the evaluation of the matrix effect. Fan, Sufang,Wang, Xiupin,Li, Peiwu,Zhang, Qi,Zhang, Wen,Fan, Sufang,Wang, Xiupin,Li, Peiwu,Zhang, Qi,Zhang, Wen,Fan, Sufang,Wang, Xiupin,Li, Peiwu.

[10]Determination of 26 Mycotoxins in Feedstuffs by Multifunctional Clean-up Column and Liquid Chromatography-Tandem Mass Spectrometry. Wang Rui-Guo,Su Xiao-Ou,Cheng Fang-Fang,Wang Pei-Long,Fan Xia,Zhang Wei. 2015

[11]Determination of Mycotoxin Biomarkers in Eggs by Liquid Chromatography-Tandem Mass Spectrometry Coupled with Matrix Solid Phase Dispersion. Zhu Run-Yue,Xu Fei,Zhu Run-Yue,Zhao Zhi-Yong,Song Su-Quan,Yang Xian-Li,Nie Dong-Xia,Wu Ai-Bo,Song Su-Quan. 2015

[12]Method development, matrix effect, and risk assessment of 49 multiclass pesticides in kiwifruit using liquid chromatography coupled to tandem mass spectrometry. Kim, Yool-Ah,Rahman, Md. Musfiqur,Shim, Jae-Han,Abd El-Aty, A. M.,Abd El-Aty, A. M.,Jeong, Ji Hoon,Shin, Ho-Chul,Jeong, Ji Hoon,Wang, Jing,Shin, SungShik. 2018

[13]Simultaneous Determination of 11 Phenolic Compounds in Perilla oil by High Performance Liquid Chromatography-Tandem Mass Spectrometry. Wu Rao,Ma Fei,Zhang Liang-Xiao,Li Pei-Wu,Zhang Wen,Zhang Qi,Li Guang-Ming,Wu Rao,Li Guang-Ming,Li Pei-Wu,Zhang Qi,Zhang Liang-Xiao,Li Pei-Wu,Ma Fei,Zhang Liang-Xiao,Li Pei-Wu,Zhang Wen,Li Guang-Ming. 2015

[14]Analysis of bronopol (2-bromo-2-nitropropan-1, 3-diol) residues in rice (Oryza sativa L.) by SPE using Bond Elut Plexa and liquid chromatography-tandem mass spectrometry. Chai, Shuang-shuang,Qin, Mei-ling,Ma, You-ning,Gao, Huan-huan,He, Qiao,Zhang, Han-tong. 2018

[15]Liquid Chromatography-Tandem Mass Spectrometry for Determination of Aflatoxin B-1, Deoxynivalenol and Zearalenone in Artificial Porcine Gastrointestinal Digestive Juice. Wang Rui-Guo,Su Xiao-Ou,Fan Xia,Wang Pei-Long,Gao Zhong-Wu,Zhang Yu. 2015

[16]Simultaneous determination of phenolic compounds in sesame oil using LC-MS/MS combined with magnetic carboxylated multi-walled carbon nanotubes. Wu, Rao,Ma, Fei,Zhang, Liangxiao,Li, Peiwu,Li, Guangming,Zhang, Qi,Zhang, Wen,Wang, Xiuping,Wu, Rao,Ma, Fei,Zhang, Liangxiao,Li, Peiwu,Li, Guangming,Zhang, Qi,Wang, Xiuping,Wu, Rao,Ma, Fei,Li, Peiwu,Li, Guangming,Zhang, Qi,Wang, Xiuping,Wu, Rao,Ma, Fei,Zhang, Liangxiao,Li, Peiwu,Zhang, Wen,Wang, Xiuping,Zhang, Liangxiao,Li, Peiwu,Li, Guangming,Zhang, Qi,Zhang, Wen,Zhang, Liangxiao,Zhang, Wen.

[17]Determination of 19 Acidic Pesticide Residues in Fruit by Dispersive Solid Phase Extraction and Liquid Chromatography-Tandem Mass Spectrometry. Jin Fen,Shi Xiao-Mei,Li Min-Jie,Shao Hua,Jin Mao-Jun,Wang Jing,Yu Zhi-Yong. 2013

[18]Determination of Flubendiamide and Chlorantraniliprole Residues in Vegetables Using Liquid Chromatography-Tandem Mass Spectrometry. Ming-Rong, Qian,Hu, Zhang,Liqin, Wu,Xiang-Yun, Wang,Hong-Mei, He,Zhi-Min, Chne,Fei, Liu. 2010

[19]A reliable liquid chromatography-tandem mass spectrometry method for simultaneous determination of multiple mycotoxins in fresh fish and dried seafoods. Sun, Wenshuo,Han, Zheng,Nie, Dongxia,Jin, Mengtong,Shi, Wen,Zhao, Zhiyong,Wu, Aibo,Sun, Wenshuo,Jin, Mengtong,Zhao, Yong,Aerts, Johan,Han, Zheng,Aerts, Johan,De Saeger, Sarah.

[20]Combinatorial approach of LC-MS/MS and LC-TOF-MS for uncovering in vivo kinetics and biotransformation of ochratoxin A in rat. Han, Zheng,Zhao, Zhiyong,Zhao, Zhihui,Wu, Aibo,Shi, Jianxin,Zhang, Dabing,Liao, Yucai,Wu, Yongning,Han, Zheng,De Saeger, Sarah.

作者其他论文 更多>>

微信小程序