Phylogenetic analysis of the bovine parainfluenza virus type 3 from cattle herds revealing the existence of a genotype A strain in China

文献类型: 外文期刊

第一作者: Wen, Yong-Jun

作者: Wen, Yong-Jun;Shi, Xin-Chuan;Wang, Feng-Xue;Wang, Wei;Zhang, Shu-Qin;Li, Guo;Song, Ni;Chen, Li-Zhi;Cheng, Shi-Peng;Wu, Hua

作者机构:

关键词: Bovine parainfluenza virus type 3 (BPIV3);Cattle;Phylogenetic analysis

期刊名称:VIRUS GENES ( 影响因子:2.332; 五年影响因子:2.0 )

ISSN: 0920-8569

年卷期: 2012 年 45 卷 3 期

页码:

收录情况: SCI

摘要: In 2009, a bovine parainfluenza virus (BPIV3), named as NM09, was isolated using MDBK cell culture from the nasal swabs of normal cattle in China. The NM09 isolate was characterized by RT-PCR and nucleotide sequence analysis. Its complete genome was 15,456 nucleotides in length. Similar to other sequenced PIV strains, the NM09 virus consisted of six non-overlapping genes, which were predicted to encode nine proteins with conserved and complementary 3' leader and 5' trailer regions, conserved gene starts, gene stops, and trinucleotide intergenic sequences. Nucleotide phylogenetic analysis of matrix and hemagglutinin-neuraminidase gene demonstrated that this NM09 isolate belonged to BPIV3 genotype A instead of the previously reported BPIV3 genotype C in China. It is implicated that the different genotypes A and C might coexist infection for a long time in China.

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