Effect of Flaxseed Oil Fortified with Vitamin E and Phytosterols on Antioxidant Defense Capacities and Lipids Profile in Rats
文献类型: 外文期刊
第一作者: Deng, Qianchun
作者: Deng, Qianchun;Yu, Xiao;Xu, Jiqu;Liu, Changsheng;Huang, Fenghong;Huang, Qingde;Yang, Jine;Deng, Qianchun;Yu, Xiao;Xu, Jiqu;Liu, Changsheng;Huang, Fenghong;Huang, Qingde;Yang, Jine
作者机构:
关键词: antioxidant defenses;flaxseed oil;lipids profiles;phytosterols;vitamin E
期刊名称:JOURNAL OF FOOD SCIENCE ( 影响因子:3.167; 五年影响因子:3.376 )
ISSN: 0022-1147
年卷期: 2012 年 77 卷 6 期
页码:
收录情况: SCI
摘要: The main proposal of this study was to evaluate in vivo whether flaxseed oils fortified with micronutrients would have beneficial effects on lipid profile and antioxidant status in high-fat fed rats. Male Wistar rats were fed synthetic diets containing 10% of flaxseed oil (FO), phytosterols (PS) fortified FO (PS-FO), vitamin E (V-E) fortified FO (V-E-FO), V-E, and PS fortified FO (V-E-PS-FO), respectively, for 4 wk. The results showed that V-E fortified FO enhanced the enzymatic (SOD and GPX) and nonenzymatic (GSH and V-E) antioxidant system, lowered the lipid peroxide (TBARS) concentration compared with FO (P < 0.05). And FO fortified with PS significantly reduced the plasma TG, TC and LDL-C levels, and hepatic TG and TC levels of rats compared with FO (P < 0.05), but had no significant effect on antioxidant defense capacities. Combined addition of V-E and PS in FO had a synergetic effect. These results indicated that flaxseed oils fortified micronutrients V-E and PS may contribute to reduce the risk factors of cardiovascular disease (CVD) by improving plasma antioxidant defenses and lipids profiles.
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