文献类型： 外文期刊
第一作者： Yao, Yang
作者： Yao, Yang;Cheng, Xuzhen;Wang, Lixia;Wang, Suhua;Ren, Guixing
作者机构：
关键词： vitexin;isovitexin;IC50
期刊名称：INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION （ 影响因子：3.833； 五年影响因子：3.859 ）
ISSN： 0963-7486
年卷期： 2012 年 63 卷 3 期
页码：
收录情况： SCI
摘要： A seventy percent ethanol from mung bean (Vigna radiatae L.) was extracted further with CH2Cl2, EtOAc and n-BuOH to afford four fractions: CH2Cl2-soluble, EtOAc-soluble, n-BuOH-soluble and residual extract fractions. When using L-3,4-dihydroxyphenylalanine as the substrate for mushroom tyrosinase, the EtOAc-soluble fractions showed the highest inhibitory activity. Two pure flavonoid compounds, vitexin and isovitexin, were isolated (using the enzyme assay-guided fractionation method) from the EtOAc-soluble fractions. Vitexin and isovitexin showed high inhibitory activities, with IC50 values of 6.3 and 5.6 mg/ml, respectively. This is the first study on the active compositions of azuki beans against mushroom tyrosinase.
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