Mesoporous silica-coated NaYF4 nanocrystals: facile synthesis, in vitro bioimaging and photodynamic therapy of cancer cells

文献类型： 外文期刊

第一作者： Liu, Xinhui

作者： Liu, Xinhui;Qian, Haisheng;Ji, Yaping;Li, Zhengquan;Shao, Yong;Hu, Yong;Tong, GuoXiu;Li, Liangchao;Guo, Weidong;Qian, Haisheng;Shao, Yong;Hu, Yong;Tong, GuoXiu;Li, Liangchao;Guo, Huichen;Guo, Huichen

作者机构：

期刊名称：RSC ADVANCES （ 影响因子：3.361； 五年影响因子：3.39 ）

ISSN： 2046-2069

年卷期： 2012 年 2 卷 32 期

页码：

收录情况： SCI

摘要： Up-conversion nanoparticles (UCNPs) that emit high-energy photons upon excitation by low-energy near-infrared (NIR) radiation are emerging as new optical nanoprobes useful in biomedicine. Herein, the one pot facile synthesis of mesoporous silica-coated NaYF4:Yb/Er nanoparticles has been achieved successfully. The as-prepared product was characterized by X-ray power diffraction (XRD), transmission electron microscopy (TEM) and Brunauer-Emmet-Teller (BET) surface area analyses, respectively. The resulting nanoparticles with a BET area of 800 m(2) g(-1) and an average pore size of 2.6 nm were spherical, highly monodispersed and stable in an aqueous system. Furthermore, the NaYF4:Yb/Er@mesoporous silica nanoparticles also displayed good biocompatibility and could be used for bio-labeling or bio-imaging. Additionally, the results of preliminary photodynamic therapy (PDT) of cancer cells indicated the NaYF4:Yb/Er@mesoporous silica nanoparticles could be used as important photosensitizer carriers for tumor therapy.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序