AGPBSim: Gene Pyramiding Breeding in Animals from Perspective of Synthetic Biology

文献类型： 外文期刊

第一作者： Xu, Lingyang

作者： Xu, Lingyang;Zhao, Fuping;Ren, Hangxing;Lu, Jian;Zhang, Li;Wei, Caihong;Du, Lixin;Zhao, Fuping

作者机构：

关键词： Breeding;allele frequencies;population;architecture;gene-pyramiding;platform

期刊名称：JOURNAL OF ANIMAL AND VETERINARY ADVANCES （ 影响因子：0.365； 五年影响因子：0.359 ）

ISSN： 1680-5593

年卷期： 2012 年 11 卷 7 期

页码：

收录情况： SCI

摘要： AGPBSim (Animal Gene-Pyramiding Breeding Simulation) is an individual-based, genetical information integrated simulation program. It was developed to investigate gene-pyramiding breeding given base population sizes, initial allele frequencies and selection strategies. The process of gene-pyramiding breeding was measured using population hamming distance, superior genotype frequency and average phenotypic values. AGPBSim is high flexible at various levels: four cross schemes and three selection strategies and trait architecture using various genotype-phenotype models were integrated in gene pyramiding breeding simulation. The GUI design of AGPBSim can facilitate design of gene-pyramiding breeding strategies by performing virtual breeding simulation on this platform.

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