Behavioral evaluation of quinestrol as a sterilant in male Brandt's voles

文献类型： 外文期刊

第一作者： Wang, Dawei

作者： Wang, Dawei;Li, Ning;Huang, Baohuan;Liu, Xiaohui;Wang, Dawei;Liu, Ming;Liu, Qi

作者机构：

关键词： Female preference;Fertility control;Lasiopodomys brandtii;Quinestrol;Social behavior

期刊名称：PHYSIOLOGY & BEHAVIOR （ 影响因子：3.244； 五年影响因子：3.4 ）

ISSN： 0031-9384

年卷期： 2011 年 104 卷 5 期

页码：

收录情况： SCI

摘要： The theoretical, ecological, physiological, and mathematical aspects of fertility control in mammals have already been well studied, but little attention has been given to the behavioral effects, especially in rodents. We investigated the effects of quinestrol, a synthetic estradiol analog, on social behavior and reproductive physiology in male Brandt's voles (Lasiopodomys brandtii). Over seven successive days, four concentration gradients of quinestrol (none, 0.001%, 0.003%, and 0.006%) were separately mixed into feed and provided to male Brandt's voles. Reproductive parameters, including the reproductive organ indexes, testosterone level and reproductive ability, were observed and collected 2 weeks after finished feeding treatment and again after 4 weeks. Dyadic social encounters and female preferences were then recorded for the control males (no quinestrol) and the highest concentration group (0.006%). Results showed that quinestrol reduced the consumption of feed. Physiological data revealed that quinestrol had also effectively reduced the reproductive organs indexes, testosterone levels, female pregnancy rates and litter size. This phenomenon was especially evident in the highest concentration group only after 2 weeks of feeding. Behavioral results showed that both frequency and duration of female preference were unbiased between control and treated males. In social conflict tests, control pairs (CC) had lower latency toward initial attack than treated pairs (IT) and pairs of one control and one treated male (CT). Among the three pairs, there was no evident difference in patterns of mutual attack and agonistic behavior. In CT pairs, sterile males have the same winning rate and agonistic behavior as control males. Our data revealed that quinestrol has anti-fertility capabilities with little behavioral side effects on Brandt's voles, which suggested quinestrol's potential as a sterilant for Brandt's voles. The palatability, however, should be improved before field practice. (C) 2011 Elsevier Inc. All rights reserved.

分类号：

  • 相关文献

[1]Characterization of nine novel microsatellite markers from Brandt's vole (Lasiopodwomys brandtii). Wang, Da-Wei,Huang, Bao-Huan,Liu, Xiao-Hui.

[2]Photodegradation of quinestrol in waters and the transformation products by UV irradiation. Tang, Tao,Qian, Kun,Shi, Tianyu,Wang, Fang,Li, Pingliang,Li, Jianqiang,Cao, Yongsong,Tang, Tao.

[3]Inclusion of quinestrol and 2,6-di-O-methyl-beta-cyclodextrin: Preparation, characterization, and inclusion mode. Ouyang, Can-Bin,Liu, Xiao-Hui,Liu, Qi,Yuan, Hao-Liang. 2013

[4]Quantitative Neuropeptidome Analysis Reveals Neuropeptides Are Correlated with Social Behavior Regulation of the Honeybee Workers. Han, Bin,Fang, Yu,Feng, Mao,Hu, Han,Qi, Yuping,Huo, Xinmei,Meng, Lifeng,Wu, Bin,Li, Jianke.

[5]Metarhizium anisopliae infection alters feeding and trophallactic behavior in the ant Solenopsis invicta. Qiu, Hua-Long,He, Yu-Rong,Lu, Li-Hua,Zalucki, M. P..

作者其他论文 更多>>

微信小程序