Anti-hyperlipidemic and antioxidant effects of alkali-extractable mycelia polysaccharides by Pleurotus eryngii var. tuolensis

文献类型： 外文期刊

第一作者： Ren, Zhenzhen

作者： Ren, Zhenzhen;Xu, Nuo;Zhang, Jianjun;Song, Xinling;Wang, Xiuxiu;Gao, Zheng;Jing, Huijuan;Li, Shangshang;Zhang, Chen;Liu, Min;Zhao, Huajie;Jia, Le;Li, Juan

作者机构：

关键词： Anti-hyperlipidemic;Antioxidative;Alkali-extractable mycelia polysaccharides;Pleurotus eryngii var. tuolensis

期刊名称：CARBOHYDRATE POLYMERS （ 影响因子：9.381； 五年影响因子：8.678 ）

ISSN： 0144-8617

年卷期： 2017 年 175 卷

页码：

收录情况： SCI

摘要： In this study, we noted that the Al-MPS from Pleurotus eryngii var. tuolensis provoked pharmacological effects on blood lipid profiles and oxidative stress. Animal studies demonstrated that Al-MPS showed potential effects on relieving hyperlipidemia and preventing oxidative stress, reflecting by decreasing the levels of serum enzyme activities (ALP, ALT and AST), restoring the activities of antioxidant enzymes (SOD, GSH-Px, CAT and T-AOC), down-regulating the MDA and LPO contents, as well as remitting the hepatic and cardiac tissues injury, respectively. The serum levels of TC, TG, LDL-C, VLDL-C, and HDL-C on mice treated with Al-MPS (500 mg/kg bw) reached 2.48 +/- 0.08, 1.24 +/- 0.03, 0.84 +/- 0.02, 0.34 +/- 0.02, and 1.80 +/- 0.03 mmol/L, which were lower/higher against the hyperlipidemia mice. The results clearly indicated that the Al-MPS could be used as a beneficial health food and potentially natural candidate medicine in preventing the high-fat emulsion-induced hyperlipidemia. (C) 2017 Elsevier Ltd. All rights reserved.

分类号：

  • 相关文献

[1]High temperature and UV-C treatments affect stilbenoid accumulation and related gene expression levels in Gnetum parvifolium. Deng, Nan,Liu, Caixia,Chang, Ermei,Ji, Jing,Yao, Xiamei,Yue, Jianyun,Jiang, Zeping,Shi, Shengqing,Bartish, Igor V.,Chen, Lanzhen,Chen, Lanzhen. 2017

[2]Pilot-scale membrane fractionation of ACE inhibitory and antioxidative peptides from ultrasound pretreated milk protein concentrate hydrolysates. Uluko, Hankie,Zhang, Shuwen,Liu, Lu,Li, Hongjuan,Cui, Wenming,Xue, Haixiao,Zhao, Lili,Lu, Jing,Lv, Jiaping,Uluko, Hankie,Sun, Yanjun. 2014

[3]Antioxidative activity of lactic acid bacteria in yogurt. Zhang, Shuwen,Liu, Lu,Su, Yanling,Li, Hongjuan,Sun, Qi,Liang, Xiao,Lv, Jiaping. 2011

[4]Effects of thermal, microwave, and ultrasound pretreatments on antioxidative capacity of enzymatic milk protein concentrate hydrolysates. Uluko, Hankie,Zhang, Shuwen,Liu, Lu,Tsakama, Madalitso,Lu, Jing,Lv, Jiaping,Uluko, Hankie,Tsakama, Madalitso.

作者其他论文 更多>>

微信小程序