Maternal dietary manganese protects chick embryos against maternal heat stress via epigenetic-activated antioxidant and anti-apoptotic abilities

文献类型： 外文期刊

第一作者： Zhu, Yongwen

作者： Zhu, Yongwen;Lu, Lin;Liao, Xiudong;Zhang, Liyang;Luo, Xugang;Zhu, Yongwen;Zhu, Yongwen;Li, Wenxiang;Ji, Cheng;Lin, Xi;Liu, Hsiao-Ching;Odle, Jack

作者机构：

关键词： epigenetics;maternal environmental hyperthermia;manganese superoxide dismutase;apoptosis;chick embryo

期刊名称：ONCOTARGET （ 影响因子：5.168； 五年影响因子：5.312 ）

ISSN： 1949-2553

年卷期： 2017 年 8 卷 52 期

页码：

收录情况： SCI

摘要： Maternal heat stress induced the aberrant epigenetic patterns resulting in the abnormal development of offspring embryos. It is unclear whether maternal dietary manganese supplementation as an epigenetic modifier could protect the chick embryonic development against maternal heat stress via epigenetic mechanisms. To test this hypothesis using an avian model, a completely randomized design with a 2 (maternal normal and high environmental temperatures of 21 and 32 degrees C, respectively) x 3 (maternal dietary manganese sources, the control diet without manganese supplementation and the control diet + 120 mg/kg as either inorganic or organic manganese) factorial arrangement was adopted. Maternal environmental hyperthermia increased mRNA expressions of heat shock proteins 90 and 70, cyclin-dependent kinase 6 and B-cell CLL/lymphoma 2-associated X protein displaying oxidative damage and apoptosis in the embryonic heart. Maternal environmental hyperthermia impaired the embryonic development associated with the alteration of epigenetic status, as evidenced by global DNA hypomethylation and histone 3 lysine 9 hypoacetylation in the embryonic heart. Maternal dietary manganese supplementation increased the heart anti-apoptotic gene B-cell CLL/lymphoma 2 expressions under maternal environmental hyperthermia and manganese superoxide dismutase enzyme activity in the embryonic heart. Maternal dietary organic Mn supplementation effectively eliminated the impairment of maternal environmental hyperthermia on the embryonic development. Maternal dietary manganese supplementation up-regulated manganese superoxide dismutase mRNA expression by reducing DNA methylation and increasing histone 3 lysine 9 acetylation of its promoter. It is suggested that maternal dietary manganese addition could protect the chick embryonic development against maternal heat stress via enhancing epigenetic-activated antioxidant and anti-apoptotic abilities.

分类号：

  • 相关文献

[1]Maternal dietary zinc supplementation enhances the epigenetic-activated antioxidant ability of chick embryos from maternal normal and high temperatures. Zhu, Yongwen,Liao, Xiudong,Lu, Lin,Zhang, Liyang,Luo, Xugang,Zhu, Yongwen,Zhu, Yongwen,Li, Wenxiang,Ji, Cheng,Lin, Xi,Liu, Hsiao-Ching,Odle, Jack. 2017

[2]Manganese elevates manganese superoxide dismutase protein level through protein kinase C and protein tyrosine kinase. Li, Sufen,Lu, Lin,Liao, Xiudong,Gao, Tianquan,Wang, Funing,Zhang, Liyang,Luo, Xugang,Li, Sufen,Xi, Lin,Liu, Songbai.

[3]Genomic structure, characterization and expression analysis of a manganese superoxide dismutase from pearl oyster Pinctada fucata. Zhang, Dianchang,Cui, Shuge,Guo, Huayang,Jiang, Shigui,Zhang, Dianchang,Jiang, Shigui.

[4]Stimulation with monochromatic green light during incubation alters satellite cell mitotic activity and gene expression in relation to embryonic and posthatch muscle growth of broiler chickens. Zhang, L.,Zhang, H. J.,Wang, J.,Wu, S. G.,Qiao, X.,Yue, H. Y.,Qi, G. H.,Zhang, L.,Yao, J. H.. 2014

[5]Effects of maternal dietary manganese and incubation temperature on hatchability, antioxidant status, and expression of heat shock proteins in chick embryos. Zhu, Y. W.,Lu, L.,Li, W. X.,Zhang, L. Y.,Luo, X. G.,Zhu, Y. W.,Ji, C.,Lin, X.,Liu, H. C.,Odle, J..

[6]Changes in relative organ weights and intestinal transporter gene expression in embryos from white Plymouth Rock and WENS Yellow Feather Chickens. Wang, Xiu-qi.

[7]Impact of maternal heat stress in conjunction with dietary zinc supplementation on hatchability, embryonic development, and growth performance in offspring broilers. Zhu, Y. W.,Lu, L.,Zhang, L. Y.,Luo, X. G.,Zhu, Y. W.,Zhu, Y. W.,Li, W. X.,Ji, C.,Lin, X.,Liu, H. C.,Odle, J..

[8]Investigating right ovary degeneration in chick embryos by transcriptome sequencing. Yu, Jianning,Yan, Leyan,Chen, Zhe,Li, Hui,Ying, Shijia,Zhu, Huanxi,Shi, Zhendan.

[9]Molecular characterizations of DNA methyltransferase 3 and its roles in temperature tolerance in the whitefly, Bemisia tabaci Mediterranean. Hong, X. -Y.,Dai, T. -M,Lu, Z. -C.,Wang, Y. -S.,Liu, W. -X.,Wan, F. -H.,Wan, F. -H.. 2018

[10]SUV39H1 mediated SIRT1 trans-repression contributes to cardiac ischemia-reperfusion injury. Yang, Guang,Zhang, Xinjian,Liang, Peng,Dai, Xin,Zeng, Sheng,Xu, Huihui,Fang, Mingming,Li, Yuehua,Xu, Dachun,Xu, Yong,Weng, Xinyu,Huan, Hailin,Xu, Dachun. 2017

[11]Mutation of the RDR1 gene caused genome-wide changes in gene expression, regional variation in small RNA clusters and localized alteration in DNA methylation in rice. Wang, Ningning,Zhang, Di,Wang, Zhenhui,Xun, Hongwei,Wang, Hui,Huang, Wei,Liu, Ying,Li, Ning,Ou, Xiufang,Zhang, Chunyu,Liu, Bao,Wang, Ningning,Ma, Jian,Lin, Xiuyun,Zhang, Chunyu,Wang, Ningning,Wang, Ming-Bo. 2014

[12]Adaptive methylation regulation of p53 pathway in sympatric speciation of blind mole rats, Spalax. Zhao, Yang,Tang, Jia-Wei,Yang, Zhi,Cao, Yi-Bin,Ren, Ji-Long,Chen, Xue-Qun,Du, Ji-Zeng,Zhao, Yang,Chen, Xue-Qun,Du, Ji-Zeng,Zhao, Yang,Chen, Xue-Qun,Du, Ji-Zeng,Zhao, Yang,Li, Kexin,Nevo, Eviatar,Cao, Yi-Bin,Ben-Abu, Yuval,Li, Kexin.

[13]Genome-Wide Differences in DNA Methylation Changes in Two Contrasting Rice Genotypes in Response to Drought Conditions. Wang, Wensheng,Qin, Qiao,Sun, Fan,Wang, Yinxiao,Xu, Dandan,Li, Zhikang,Fu, Binying,Xu, Dandan,Li, Zhikang,Fu, Binying. 2016

[14]Specific but interdependent functions for Arabidopsis AGO4 and AGO6 in RNA-directed DNA methylation. Duan, Cheng-Guo,Zhang, Huiming,Tang, Kai,Zhu, Xiaohong,Hou, Yueh-Ju,Wang, Bangshing,Lang, Zhaobo,Zhao, Yang,Wang, Xingang,Wang, Pengcheng,Zhu, Jian-Kang,Qian, Weiqiang,Zhao, Yang,Zhu, Jian-Kang,Zhou, Jianping,Liang, Gaimei,Liu, Na,Wang, Chunguo.

[15]Alien DNA Introgression into Rice Causes Heritable Alterations in DNA Methylation Patterns in an Active Retrotransposon Tos17. Dong, YZ,Liu, ZL,Dong, YS,Han, FR,He, MY,Hao, S,Liu, B.

[16]A transposon-directed epigenetic change in ZmCCT underlies quantitative resistance to Gibberella stalk rot in maize. Wang, Chao,Yang, Qin,Li, Yipu,Guo, Yanling,Zhang, Dongfeng,Ma, Xuena,Xu, Mingliang,Wang, Weixiang,Song, Wei,Zhao, Jiuran.

[17]The Caspase Pathway of Linoelaidic Acid (9t, 12t-C18:2)-Induced Apoptosis in Human Umbilical Vein Endothelial Cells. Bin, Qiu,Rao, Huan,Hu, Jiang-Ning,Liu, Rong,Fan, Ya-Wei,Li, Jing,Deng, Ze-Yuan,Zhong, Xianfeng,Bin, Qiu,Du, Fang-Ling. 2013

[18]Detection of DNA ladder during cotyledon senescence in cotton. Q.E. XIE,I.D. LIU,S.X. YU,R.F. WANG,Z.X. FAN,Y.G. WANG,F.F. SHEN.

[19]Effects of species and cellular activity of oviductal epithelial cells on their dialogue with co-cultured mouse embryos. Tan, Xiu-Wen,Ma, Suo-Feng,Yu, Jian-Ning,Zhang, Xia,Lan, Guo-Cheng,Liu, Xin-Yong,Han, Zheng-Bin,Tan, Jing-He. 2007

[20]Oxidative Stress-Mediated Cytotoxicity of Cadmium in Chicken Splenic Lymphocytes. Li, Jin-Long,Tang, Zhao-Xin,Li, Jin-Long,Li, Shu,Xu, Shi-Wen,Li, Hui-Xin,Wang, Xiao-Long. 2010

作者其他论文 更多>>

微信小程序