Evaluation on Infectivity of Babesia microti to Domestic Animals and Ticks Outside the Ixodes Genus

文献类型： 外文期刊

第一作者： Wu, Jiajun

作者： Wu, Jiajun;Cao, Jie;Zhou, Yongzhi;Zhang, Houshuang;Gong, Haiyan;Zhou, Jinlin;Zhou, Jinlin

作者机构：

关键词： Babesia microti;experimental infection;domestic animals;tick;Haemaphysalis longicornis

期刊名称：FRONTIERS IN MICROBIOLOGY （ 影响因子：5.64； 五年影响因子：6.32 ）

ISSN： 1664-302X

年卷期： 2017 年 8 卷

页码：

收录情况： SCI

摘要： Babesiosis caused by Babesia microti parasite is an emerging tick borne zoonotic disease that was confirmed recently in China. To understand the epidemiology characteristics of this emerging disease, infectivity of B. microti to domestic animals and ticks outside the genus Ixodes was evaluated in this study. Different domestic animals, chick, pig, goat, dog and the reference host rat were experimentally inoculated with B. microti-infected erythrocytes and the parasite infection was monitored daily by blood smear observation, real-time PCR detection, nested-PCR and special antibody responses during 55 days period. The results showed that rats infected with B. microti showed a typical sustained infection with strongly antibody responses; however, both goats and dogs infected with B. microti only showed transient antibody responses and the parasite was not found by blood smear observation or PCR; neither the parasite nor the special antibodies were detected in experimental chicks and pigs. On the other hand, the present study also experimentally investigated the infectivity of B. microti to Rhipicephalus haemaphysaloides, Haemaphysalis longicornis, and Hyalomma asiaticum three species of ticks outside the genus Ixodes and the transmission experiment of B. microti between H. longicornis ticks and mice. Results showed that B. microti can be detected in the nymph and adult of these species after molting from engorged tick fed on infected mice, but the parasite was not detected in larvae hatching from eggs of engorged female tick fed on the infected mice. Transmission of B. microti to mice by infected H. longicornis nymphs was confirmed. These results indicated that these domestic animals do not have reservoir competence for B. microti, however, three species of ticks out of the genus Ixodes, common in China were successfully infected by B. microti, with H. longicornis showing the potential of transmitting the parasite to the vertebrate host.

分类号：

  • 相关文献

[1]Epidemiology of toxoplasmosis: role of the tick Haemaphysalis longicornis. Zhou, Yongzhi,Zhang, Houshuang,Cao, Jie,Gong, Haiyan,Zhou, Jinlin,Zhou, Jinlin. 2016

[2]Characterization of one sheep border disease virus in China. Mao, Li,Liu, Xia,Li, Wenliang,Yang, Leilei,Zhang, Wenwen,Jiang, Jieyuan,Mao, Li,Liu, Xia,Li, Wenliang,Yang, Leilei,Zhang, Wenwen,Jiang, Jieyuan,Mao, Li,Liu, Xia,Li, Wenliang,Yang, Leilei,Zhang, Wenwen,Jiang, Jieyuan. 2015

[3]Combined DNA vaccines formulated either in DDA or in saline protect cattle from Mycobacterium bovis infection. Cai, H,Tian, X,Hu, XD,Li, SX,Yu, DH,Zhu, YX.

[4]Exudative epidermitis of piglets caused by non-toxigenic Staphylococcus sciuri. Lu, Lixin,He, Kongwang,Ni, Yanxiu,Yu, Zhengyu,Mao, Aihua,Lu, Lixin,He, Kongwang,Ni, Yanxiu,Yu, Zhengyu,Mao, Aihua.

[5]Histopathological and cytopathological findings in minipigs infected with Streptococcus suis serotype 2. Xie, Chun,Hou, Yi-Xuan,Zhao, Yu-Ting,Li, Cai-Ying,Su, Xue,Yue, Xiu-Wei,Yang, Wei-Jun,Yuan, Cong-Li,Cu, Li,Hua, Xiu-Guo,Yang, Zhi-Biao,Cai, Xue-Hui,Wang, Shu-Jie,Liu, Yong-Gang,Li, Cai-Ying,Li, Pei-Feng,Li, Yun-Zhang,Su, Xue,Yang, Wei-Jun.

[6]Diagnosis of Peste des Petits Ruminants in Wild and Domestic Animals in Xinjiang, China, 2013-2016. Li, J.,Li, L.,Wu, X.,Liu, F.,Zou, Y.,Wang, Q.,Liu, C.,Bao, J.,Wang, Z.,Wang, W.,Ma, W.,Lin, H.,Huang, J.,Zheng, X.. 2017

[7]Progress of genome wide association study in domestic animals. Zhang, Hui,Wang, Zhipeng,Wang, Shouzhi,Li, Hui,Zhang, Hui,Wang, Zhipeng,Wang, Shouzhi,Li, Hui. 2012

[8]Nested-PCR assay for detection of Schistosoma japonicum infection in domestic animals. Zhang, Xin,He, Chuan-Chuan,Liu, Jin-Ming,Li, Hao,Lu, Ke,Fu, Zhi-Qiang,Zhu, Chuan-Gang,Hong, Yang,Jin, Ya-Mei,Lin, Jiao-Jiao,Liu, Yi-Ping,Tong, Lai-Bao,Zhou, De-bao,Zha, Li,Lin, Jiao-Jiao. 2017

[9]A candidate recombinant antigen for diagnosis of schistosomiasis japonica in domestic animals. Feng, Jintao,Xu, Rui,Zhang, Xin,Han, Yu,He, Chuanchuan,Lu, Chao,Hong, Yang,Lu, Ke,Li, Hao,Jin, Yamei,Lin, Jiaojiao,Liu, Jinming,Lin, Jiaojiao.

[10]Molecular Detection of Tick-Borne Rickettsiales in Goats and Sheep from Southeastern China. Ge, Yan,Yin, Hongmei,Pan, Weiqing,Rikihisa, Yasuko,Yin, Hong. 2016

[11]Molecular characterization of Babesia microti thioredoxin (BmTrx2) and its expression patterns induced by antiprotozoal drugs. Huang, Jingwei,Xiong, Kang,Zhang, Houshuang,Zhao, Yanzhen,Cao, Jie,Gong, Haiyan,Zhou, Yongzhi,Zhou, Jinlin. 2018

[12]Expression of truncated Babesia microti apical membrane protein 1 and rhoptry neck protein 2 and evaluation of their protective efficacy. Wang, Guanbo,Efstratiou, Artemis,Moumouni, Paul Franck Adjou,Liu, Mingming,Jirapattharasate, Charoonluk,Guo, Huanping,Gao, Yang,Suzuki, Hiroshi,Igarashi, Ikuo,Xuan, Xuenan,Cao, Shinuo,Zhou, Mo.

[13]Identification and characterization of an interspersed repeat antigen of Babesia microti (BmIRA). Cao, Shinuo,Luo, Yuzi,Aboge, Gabriel Oluga,Terkawi, Mohamad Alaa,Masatani, Tatsunori,Suzuki, Hiroshi,Igarashi, Ikuo,Nishikawa, Yoshifumi,Xuan, Xuenan,Luo, Yuzi.

[14]Identification of 2-Cys Peroxiredoxin (BmTPx-2) as Antioxidant Active Molecule from Babesia microti. Hai, Xunan,Zhang, Houshuang,Wang, Zhonghua,Gong, Haiyan,Cao, Jie,Zhou, Yongzhi,Zhou, Jinlin,Zhou, Jinlin. 2017

[15]Babesia microti Aldo-keto Reductase-Like Protein Involved in Antioxidant and Anti-parasite Response. Huang, Qiang,Cao, Jie,Zhou, Yongzhi,Huang, Jingwei,Gong, Haiyan,Zhang, Houshuang,Zhou, Jinlin,Zhu, Xing-Quan,Zhu, Xing-Quan,Zhou, Jinlin. 2017

[16]Identification of a thioredoxin reductase from Babesia microti during mammalian infection. Zhao, Shaoruo,Gong, Haiyan,Zhou, Yongzhi,Zhang, Houshuang,Cao, Jie,Zhou, Jinlin,Zhou, Jinlin.

[17]Identification and functional study of a novel 2-cys peroxiredoxin (BmTPx-1) of Babesia microti. Zhang, Houshuang,Wang, Zhonghua,Gong, Haiyan,Cao, Jie,Zhou, Yongzhi,Zhou, Jinlin,Zhou, Jinlin.

[18]Experimental transmission of an unnamed bovine Babesia by Hyalomma spp., Haemaphysalis longicornis and Boophilus microplus. Luo, JX,Chen, FY,Lu, WS,Guan, GQ,Ma, ML,Yin, H. 2003

[19]Babesia sp. BQ1 (Lintan): Molecular evidence of experimental transmission to sheep by Haemaphysalis qinghaiensis and Haemaphysalis longicornis. Guan, Guiquan,Moreau, Emmanuelle,Chauvin, Alain,Guan, Guiquan,Liu, Junlong,Hao, Xuefen,Ma, Miling,Luo, Jianxun,Yin, Hong.

[20]A secreted cystatin from the tick Haemaphysalis longicornis and its distinct expression patterns in relation to innate immunity. Zhou, Jinlin,Ueda, Mami,Umemiya, Rika,Battsetseg, Badgar,Boldbaatar, Damdinsuren,Xuan, Xuenan,Fujisaki, Kozo.

作者其他论文 更多>>

微信小程序