Effect of streptozocin-induced diabetes mellitus on expression of methionine sulfoxide reductases and accumulation of their substrates in mouse lenses

文献类型: 外文期刊

第一作者: Li, Yi

作者: Li, Yi;Huang, Kaixun;Zhang, Wen;Li, Peiwu

作者机构:

关键词: cataract;streptozotocin;diabetes;methionine sulfoxide reductase;oxidative stress;lens

期刊名称:EXPERIMENTAL EYE RESEARCH ( 影响因子:3.467; 五年影响因子:3.811 )

ISSN: 0014-4835

年卷期: 2011 年 92 卷 5 期

页码:

收录情况: SCI

摘要: To determine the influences of early-stage diabetes mellitus on methionine sulfoxide reductases (Msrs) expression in lenses, streptozocin (STZ)-induced diabetic mice as animal models were used in this study. The results showed that the contents of methionine sulfoxide (MetO), protein carbonyl (PC) and Malondialdehyde (MDA) in the lenses of STZ-induced diabetic mice after 14 days were significantly higher than that in the normal control, level of total sulfhydryl groups (TSH) was 60% of normal control, and mRNA expressing levels of the MsrA and MsrBs were significantly decreased compared with normal group, as was the expression of MsrB1 protein. These results suggest that STZ not only causes increased oxidative stress, but also suppresses Msr mRNA and MsrB1 protein expression during early-stage diabetes in mice. However, the mechanism remains to research. (c) 2011 Elsevier Ltd. All rights reserved.

分类号:

  • 相关文献

[1]The PP2A-A beta Gene is Regulated by Multiple Transcriptional Factors Including Ets-1, SP1/SP3, and RXR alpha/beta. Liu, J.,Chen, P. -C.,Hu, W. -F.,Hu, X.,Liu, W. -B.,Xiao, Y. -M.,Liang, S. -P.,Liu, Y.,Liu, S. -J.,Li, D. W. -C.,Liu, J.,Ji, W.,Sun, S.,Zhang, L.,Chen, H. -G.,Zhang, X.,Gong, L.,Deng, M.,Chen, P. -C.,Hu, W. -F.,Hu, X.,Liu, J.,Woodward, Z.,Li, D. W. -C.,Li, D. W. -C.,Liu, J.,Sun, S.,Zhang, L.,Chen, H. -G.,Mao, Y.,Liu, L.,Gong, L.,Deng, M.,Deng, M.,Chen, L.,Han, W. -J.. 2012

[2]The p53-Bak apoptotic signaling axis plays an essential role in regulating differentiation of the ocular lens. Deng, M.,Ji, W.,Zhang, X.,Gong, L.,Hu, X.,Hu, W.,Xiao, L.,Li, D. W. -C.,Chen, P.,Liu, F.,Fu, S.,Tang, H.,Fu, Y.,Xiong, Z.,Hui, S.,Hu, X.,Hu, W.,Xiao, L.,Liu, W. -B.,Xiao, Y. -M.,Liu, S. -J.,Liu, Y.,Li, D. W. -C.,Zhang, L.,Sun, S.,Liu, J.,Li, D. W. -C..

[3]Protein serine/threonine phosphotase-1 is essential in governing normal development of vertebrate eye. Liu, F. -Y.,Tang, X. -C.,Wu, K. -L.,Wu, M. -X.,Liu, X. -L.,Luo, L. -X.,Yu, M. -B.,Liu, Y. -Z.,Li, D. W. -C.,Liu, W. -B.,Yan, Q.,Nie, L.,Zhang, X. -W.,Hu, X. -H.,Hu, W. -F.,Liu, S. -J.,Li, D. W. -C.,Chen, H. -G.,Liu, J.,Ji, W. -K.,Hu, X. -H.,Hu, W. -F.,Woodward, Z.,Li, D. W. -C.,Chen, H. -G.,Liu, J.,Li, D. W. -C..

[4]The tumor suppressor p53 regulates c-Maf and Prox-1 to control lens differentiation. Liu, F. -Y.,Tang, X. -C.,Wu, K.,Wu, M. -X.,Liu, X. -L.,Yu, M. -B.,Liu, Y.,Li, D. W. -C.,Deng, M.,Chen, P.,Ji, W.,Zhang, X.,Gong, L.,Woodward, Z.,Liu, J.,Zhang, L.,Sun, S.,Liu, J. -P.,Li, D. W. -C.,Deng, M.,Deng, M.,Gong, L.,Liu, J.,Zhang, L.,Sun, S.,Li, D. W. -C..

[5]Mulberry (Morus L.) methionine sulfoxide reductase gene cloning, sequence analysis, and expression in plant development and stress response. Tong, Wei,Zhang, Yinghua,Wang, Heng,Li, Feng,Liu, Zhaoyue,Wang, Yuhua,Fang, Rongjun,Zhao, Weiguo,Li, Long,Wang, Yuhua,Zhao, Weiguo,Li, Long,Fang, Rongjun.

[6]Transgenic Expression and Identification of Recombinant Human Proinsulin in Peanut. Zheng Ling,Wang Yu,Wan Shu-Bo,Peng Zhen-Ying,Bi Yu-Ping,Zheng Ling,Wang Yu,Bian Fei,Wan Shu-Bo,Peng Zhen-Ying,Zheng Ling,Wang Yu,Bian Fei,Wan Shu-Bo,Peng Zhen-Ying,Bi Yu-Ping,Jiao Qi-Qing,Qu Shu-Jie,Wan Shu-Bo,Bi Yu-Ping. 2016

[7]Production of Proinsulin in Marker-Free Transgenic Tobacco Plants Using CRE/loxP System. Zheng, L.,Wang, Y.,Wan, S. B.,Bi, Y. P.,Zheng, L.,Peng, Z. Y.,Wang, Y.,Bian, F.,Wan, S. B.,Bi, Y. P.,Zheng, L.,Peng, Z. Y.,Wang, Y.,Bian, F.,Wan, S. B.,Bi, Y. P.,Jiao, Q. Q.,Qu, S. J.,Wan, S. B.,Bi, Y. P..

[8]Severe hypertriglyceridemia and hypercholesterolemia accelerating renal injury: a novel model of type 1 diabetic hamsters induced by short-term high-fat/high-cholesterol diet and low-dose streptozotocin. He, Liang,Fu, Xin,Huang, Mingshu,Hao, Lili,Li, Rui,Li, Rui. 2015

[9]Enhancement of the Pharmacological Efficacy of FGF-21 by Genetic Modification and PEGylation. Ye, Xianlong,Qi, Jianying,Ren, Guiping,Zhu, Shenglong,Wu, Yunzhou,Yu, Dan,Liu, Mingyao,Li, Deshan,Sun, Guopeng,Zhao, Jingzhuang,Li, Deshan. 2013

[10]Effects of flaxseed oil on anti-oxidative system and membrane deformation of human peripheral blood erythrocytes in high glucose level. Huang, Qingde,Xu, Jiqu,Deng, Qianchun,Huang, Fenghong,Yang, Wei,Fu, Juan,Yu, Miao,Wang, Di,Yao, Ping,Liu, Liegang,Yang, Wei,Fu, Juan,Yu, Miao,Wang, Di,Yao, Ping,Liu, Liegang. 2012

[11]Protective effect of Schisandrae chinensis oil on pancreatic beta-cells in diabetic rats. An, Liping,Wang, Chunmei,Han, Xiao,Xu, Guangyu,Yuan, Guangxin,Li, Hongyu,Sheng, Yu,Wang, Manli,Sun, Jingbo,Zhan, Jinzhuo,Sun, Hui,Li, Na,Du, Peige,Wang, Yingping,Fan, Meizhen,Ding, Fuxiang. 2015

[12]Antibacterial Activity of Polyphenols: Structure-Activity Relationship and Influence of Hyperglycemic Condition. Xie, Yixi,Chen, Jing,Xiao, Aiping,Liu, Liangliang,Xie, Yixi. 2017

[13]Therapeutic Strategies of Plant-derived Compounds for Diabetes Via Regulation of Monocyte Chemoattractant Protein-1. Czemplik, Magdalena,Kulma, Anna,Szopa, Jan,Wang, Yu Fu,Szopa, Jan,Szopa, Jan.

[14]Comparative Evaluation of Quercetin, Isoquercetin and Rutin as Inhibitors of alpha-Glucosidase. Li, Yan Qin,Zhou, Feng Chao,Gao, Fei,Bian, Jun Sheng,Shan, Fang. 2009

[15]Improved method for quantitative analysis of methylated phosphatidylethanolamine species and its application for analysis of diabetic-mouse liver samples. Wang, Miao,Kim, Geun Hyang,Altarejos, Judith,Han, Xianlin,Wei, Fang,Chen, Hong.

[16]Multi-transgenic minipig models exhibiting potential for hepatic insulin resistance and pancreatic apoptosis. Kong, Siyuan,Ruan, Jinxue,Xin, Leilei,Fan, Junhua,Xia, Jihan,Liu, Zhiguo,Mu, Yulian,Yang, Shulin,Li, Kui.

[17]Effect of consumption of micronutrient enriched wheat steamed bread on postprandial plasma glucose in healthy and type 2 diabetic subjects. Lan Su-Que,Meng Ya-Ning,Li Xing-Pu,Zhang Ye-Lun,Song Guang-Yao,Ma Hui-Juan,Li Xing-Pu,Zhang Ye-Lun,Lan Su-Que. 2013

[18]Antidiabetic Activities of Ethanol Extract of Dry Matters of Culture Broth of Coriolus versiolor in Submerged Culture. Zhang, Zuofa,Lv, Guoying,Pan, Huijuan,Fan, Leifa,dos Santos, Leandro Freire,Soccol, Carlos Ricardo,Thomaz-Soccol, Vanete,Fan, Menghai,dos Santos, Leandro Freire,Fan, Menghai,Soccol, Carlos Ricardo.

[19]Effects on the bones of vanadyl acetylacetonate by oral administration: a comparison study in diabetic rats. Zhang, Shuang-Qing,Chen, Guo-Hua,Lu, Wan-Liang,Zhang, Qiang. 2007

[20]Mosquitocidal, Antimalarial and Antidiabetic Potential of Musa paradisiaca-Synthesized Silver Nanoparticles: In Vivo and In Vitro Approaches. Anbazhagan, Priya,Murugan, Kadarkarai,Jaganathan, Anitha,Sujitha, Vasu,Samidoss, Christina Mary,Jayashanthani, Sudalaimani,Amuthavalli, Pandian,Murugan, Kadarkarai,Higuchi, Akon,Kumar, Suresh,Wei, Hui,Nicoletti, Marcello,Canale, Angelo,Benelli, Giovanni,Benelli, Giovanni.

作者其他论文 更多>>