DNA polymorphism of introns 1 and 2 of Prolactin Receptor Gene and its association with litter size in goats

文献类型： 外文期刊

第一作者： Di Ran

作者： Di Ran;Chu Ming-Xing;Cao Gui-Ling;Feng Tao;Fang Li;Yin Jing;Zhou Zhong-Xiao

作者机构：

关键词： association analysis;goats;litter size;Prolactin Receptor Gene;SSCP

期刊名称：ANIMAL SCIENCE PAPERS AND REPORTS （ 影响因子：1.078； 五年影响因子：1.097 ）

ISSN： 0860-4037

年卷期： 2011 年 29 卷 4 期

页码：

收录情况： SCI

摘要： The prolactin receptor (PRLR) gene was studied as a candidate gene for the high prolificacy of Jining Grey goats. Polymorphisms in intron 1 and intron 2 of PRLR gene were detected in high prolificacy (Jining Grey) and low prolificacy (Boer, Wendeng dairy, Liaoning Cashmere and Beijing) native goats using PCR-SSCP. For intron 1, five genotypes (AA, AH, AK, HH and HK) were identified in Jining Grey goats, and two (AA and AK) in the other four breeds. The Jining Grey does of genotype HH, HK, AH and AK delivered by 0.65, 0.62, 0.59 and 0.57 more kids (P<0.01) than those of genotype AA, respectively. For intron 2, three genotypes (CC, CD and DD) were detected in Boer goats, and two (CC and CD) in the other four breeds. The Jining Grey does of genotype CD delivered by 0.55 (P<0.01) more kids than those of genotype CC.

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