Simplified Method for Determination of Mancozeb Residues in Apple Using Ultra Performance Liquid Chromatography-Mass Spectrometry
文献类型: 外文期刊
第一作者: Dong Feng-Shou
作者: Dong Feng-Shou;Liu Xin-Gang;Cheng Li;Wang Chen-Rui;Zheng Yong-Quan;Chen Wu-Ying;Liao Xiao-Lan;Qin Dong-Mei
作者机构:
关键词: Ultra performance liquid chromatography-mass spectrometry;Dispersion solid phase extraction;Methylation;Mancozeb;Apple
期刊名称:CHINESE JOURNAL OF ANALYTICAL CHEMISTRY ( 影响因子:1.134; 五年影响因子:0.909 )
ISSN: 0253-3820
年卷期: 2010 年 38 卷 4 期
页码:
收录情况: SCI
摘要: It is difficult to directly determine mancozeb because they are insoluble in general solvents. And the residue analysis in agricultural and crops is more complicated currently. In this study, a rapid method has been developed for the determination of germicide mancozeb residues in apple. The mancozeb of apple sample, which was methylated by dimethyl sulfate, was extracted by the Quick, easy, cheap, effective, rugged and safe method and detected by ultra performance liquid chromatography-mass spectrometry under multiple reaction monitoring mode, then quantified by matrix-match standard solution. The qualitative results were obtained based on retention time, the precursor ion and two daughter ions, and the quantitation results were on the intension of the characteristic m/z 241/117 ion and m/z 241/193 ion. Average recoveries of mancozeb in apple samples were found in the range of 88.7% - 109.4% at four spiking levels from 0.005 to 0.5 mg/kg with relative standard deviations of 5.9% - 8.7%. Limits of detection of mancozeb were 2.5 x 10(-4) mg/kg, while limits of quantification were 8.3 x 10(-4) mg/kg. The method is simple, rapid, and accurate, and can meet the requirements of the domestic and international legislation.
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