文献类型： 外文期刊
第一作者： Jin, Ya-mei
作者： Jin, Ya-mei;Lu, Ke;Zhou, Wei-Fang;Fu, Zhi-Qiang;Liu, Jin-Ming;Shi, Yao-Jun;Li, Hao;Lin, Jiao-Jiao
作者机构：
期刊名称：CLINICAL AND VACCINE IMMUNOLOGY （ 影响因子：3.233； 五年影响因子：2.562 ）
ISSN： 1556-6811
年卷期： 2010 年 17 卷 3 期
页码：
收录情况： SCI
摘要： The most important animal reservoirs of Schistosoma japonicum in China are bovines. Diagnosis and control of bovine schistosomiasis is critical for reducing the prevalence of the disease. We screened defined diagnostic antigens that have the potential to increase the sensitivity and specificity of serological assays and to distinguish between active and prior infections. Five recombinant proteins with the potential to be diagnostic antigens were compared to the native soluble egg antigen preparation by enzyme-linked immunosorbent assay (ELISA). We evaluated the potentials of the recombinant proteins for discriminating active from prior infections, as well as the therapeutic efficacy of the established ELISA technique.
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