H5N1 influenza viruses: outbreaks and biological properties

文献类型： 外文期刊

第一作者： Neumann, Gabriele

作者： Neumann, Gabriele;Kawaoka, Yoshihiro;Chen, Hualan;Gao, George F.;Shu, Yuelong;Kawaoka, Yoshihiro

作者机构：

关键词： influenza;H5N1;China;human infections;HA;PB2;NS1

期刊名称：CELL RESEARCH （ 影响因子：25.617； 五年影响因子：25.924 ）

ISSN： 1001-0602

年卷期： 2010 年 20 卷 1 期

页码：

收录情况： SCI

摘要： All known subtypes of influenza A viruses are maintained in wild waterfowl, the natural reservoir of these viruses. Influenza A viruses are isolated from a variety of animal species with varying morbidity and mortality rates. More importantly, influenza A viruses cause respiratory disease in humans with potentially fatal outcome. Local or global outbreaks in humans are typically characterized by excess hospitalizations and deaths. In 1997, highly pathogenic avian influenza viruses of the H5N1 subtype emerged in Hong Kong that transmitted to humans, resulting in the first documented cases of human death by avian influenza virus infection. A new outbreak started in July 2003 in poultry in Vietnam, Indonesia, and Thailand, and highly pathogenic avian H5N1 influenza viruses have since spread throughout Asia and into Europe and Africa. These viruses continue to infect humans with a high mortality rate and cause worldwide concern of a looming pandemic. Moreover, H5N1 virus outbreaks have had devastating effects on the poultry industries throughout Asia. Since H5N1 virus outbreaks appear to originate from Southern China, we here examine H5N1 influenza viruses in China, with an emphasis on their biological properties.

分类号：

  • 相关文献

[1]Innate Sensing of Influenza A Virus Hemagglutinin Glycoproteins by the Host Endoplasmic Reticulum (ER) Stress Pathway Triggers a Potent Antiviral Response via ER-Associated Protein Degradation. Wang, Bin,Zheng, Yong-Hui,Frabutt, Dylan A.,Riaz, Sana,Schwartz, Richard C.,Zheng, Yong-Hui. 2018

[2]Protective efficacy of an H1N1 cold-adapted live vaccine against the 2009 pandemic H1N1, seasonal H1N1, and H5N1 influenza viruses in mice. Shi, Jianzhong,Wen, Zhiyuan,Guo, Jing,Zhang, Ying,Deng, Guohua,Jiang, Yongping,Bu, Zhigao,Chen, Hualan,Shu, Yuelong,Wang, Dayan,Kawaoka, Yoshihiro.

[3]The influenza virus gene pool in a poultry market in South Central China. Liu, M,He, SQ,Walker, D,Zhou, NN,Perez, DR,Mo, B,Li, F,Huang, XT,Webster, RG,Webby, RJ. 2003

[4]Fusion of C3d with hemagglutinin enhances protective immunity against swine influenza virus. Li, Guo-Xin,Tian, Zhi-Jun,Yu, Hai,Jin, Yuan-Yuan,Hou, Shao-Hua,Zhou, Yan-Jun,Liu, Tian-Qiang,Hu, Shou-Ping,Tong, Guang-Zhi,Li, Guo-Xin,Tong, Guang-Zhi,Li, Guo-Xin,Yu, Hai,Zhou, Yan-Jun,Tong, Guang-Zhi.

[5]H5N1 avian influenza in China. Chen HuaLan,Chen HuaLan. 2009

[6]The NS1 protein of H5N6 feline influenza virus inhibits feline beta interferon response by preventing NF-kappa B and IRF3 activation. Wang, Lifang,Fu, Xinliang,Zheng, Yun,Zhou, Pei,Fang, Bo,Huang, San,Zhang, Xin,Li, Shoujun,Tian, Jin,Chen, Jidang,Cao, Zongxi,Wang, Lifang,Fu, Xinliang,Zheng, Yun,Zhou, Pei,Fang, Bo,Huang, San,Zhang, Xin,Li, Shoujun,Wang, Lifang,Zheng, Yun,Zhou, Pei,Huang, San,Zhang, Xin,Li, Shoujun. 2017

[7]Influenza a virus NS1 protein induced A20 contributes to viral replication by suppressing interferon-induced antiviral response. Feng, Wenjing,Sun, Xiaoning,Zhang, Maolin,Guan, Zhenhong,Duan, Ming,Shi, Ning.

[8]Cross-Glade protective immune responses of NS1-truncated live attenuated H5N1 avian influenza vaccines. Shi, Shaohua,Chen, Sujuan,Han, Weizhou,Wu, Bai,Zhang, Xiaojian,Tang, Ying,Wang, Xiao,Zhu, Yinbiao,Peng, Daxin,Liu, Xiufan,Shi, Shaohua,Chen, Sujuan,Han, Weizhou,Wu, Bai,Zhang, Xiaojian,Tang, Ying,Wang, Xiao,Zhu, Yinbiao,Peng, Daxin,Liu, Xiufan,Shi, Shaohua,Chen, Sujuan,Han, Weizhou,Wu, Bai,Zhang, Xiaojian,Tang, Ying,Wang, Xiao,Zhu, Yinbiao,Peng, Daxin,Liu, Xiufan,Shi, Shaohua.

[9]Mitochondrial antiviral signaling adaptor mediated apoptosis in H3N2 swine influenza virus infection is inhibited by viral protein NS1 in vitro. Zhang, Jinqiu,Miao, Jinfeng,Lu, Chengping,Zhang, Jinqiu,Hou, Jibo.

[10]Annexin A2 (ANXA2) interacts with nonstructural protein 1 and promotes the replication of highly pathogenic H5N1 avian influenza virus. Ma, Yong,Sun, Jiashan,Gu, Linlin,Bao, Hongmei,Zhao, Yuhui,Tian, Guobin,Wang, Xiurong,Chen, Hualan,Shi, Lin,Yao, Wei. 2017

[11]Strategies Exploited by Influenza A Virus for Evading Immune Responses. Zhao Pu,Zheng Yu-Shu,Jia Bei-Bei,Liu Xing-You,Qiao Chuan-Ling. 2008

[12]The non-structural (NS1) protein of influenza A virus associates with p53 and inhibits p53-mediated transcriptional activity and apoptosis. Wang, Xiaodu,Shen, Yang,Qiu, Yafeng,Shi, Zixue,Shao, Donghua,Chen, Peijun,Tong, Guangzhi,Ma, Zhiyong,Qiu, Yafeng,Shao, Donghua,Ma, Zhiyong. 2010

[13]Concurrent infections of pseudorabies virus and porcine bocavirus in China detected by duplex nanoPCR. Luo, Yakun,Liang, Lin,Zhou, Ling,Cui, Shangjin,Luo, Yakun,Cui, Shangjin,Zhao, Kai.

[14]High genetic and antigenic similarity between a swine H3N2 influenza A virus and a prior human influenza vaccine virus: A possible immune pressure-driven cross-species transmission. Pan, Chungen,Jiang, Shibo,Wang, Guiping,Liao, Ming,Zhang, Gui-Hong. 2009

[15]Detection of influenza viral gene in European starlings and experimental infection. Qin, Zhuoming,Clements, Teresa,Wang, Leyi,Khatri, Mahesh,Pillai, Smitha P. S.,LeJeune, Jeffrey T.,Lee, Chang-Won,Qin, Zhuoming,Zhang, Yan,LeJeune, Jeffrey T.,Lee, Chang-Won. 2011

[16]Recombinant Newcastle disease virus expressing H9 HA protects chickens against heterologous avian influenza H9N2 virus challenge. Nagy, Abdou,Lee, Jinhwa,Henningson, Jamie,Li, Yuhao,Ma, Jingjiao,Duff, Michael,Li, Yonghai,Lang, Yuekun,Yang, Jianmei,Richt, Juergen,Ma, Wenjun,Nagy, Abdou,Abdallah, Fatma,Ali, Ahmed,Mena, Ignacio,Garcia-Sastre, Adolfo,Mena, Ignacio,Garcia-Sastre, Adolfo,Yang, Jianmei,Garcia-Sastre, Adolfo.

[17]Expression analyses and antiviral properties of the Beijing-You and White Leghorn myxovirus resistance gene with different amino acids at position 631. Du, L. X.,Zhao, G. P.,Zhang, C. S..

[18]Blockage of regulatory T cells augments induction of protective immune responses by influenza virus-like particles in aged mice. Wen, Zhiyuan,Bu, Zhigao,Wang, Xi,Dong, Ke,Zhang, Huizhong,Wang, Xi,Dong, Ke,Zhang, Huizhong,Wen, Zhiyuan,Wang, Xi,Dong, Ke,Ye, Ling,Yang, Chinglai. 2017

[19]Two different genotypes of H1N2 swine influenza virus isolated in northern China and their pathogenicity in animals. Yang, Huanliang,Chen, Yan,Qiao, Chuanling,Xin, Xiaoguang,Bu, Zhigao,Chen, Hualan,Xu, Chuantian,Yan, Minghua.

[20]An M2e-based synthetic peptide vaccine for influenza A virus confers heterosubtypic protection from lethal virus challenge. Ma, Ji-Hong,Yang, Fu-Ru,Yu, Hai,Zhou, Yan-Jun,Li, Guo-Xin,Huang, Meng,Wen, Feng,Tong, Guangzhi. 2013

作者其他论文 更多>>

微信小程序