ASSOCIATION AND HAPLOTYPE ANALYSIS OF purH GENE WITH INOSINE MONOPHOSPHATE CONTENT IN CHICKENS

文献类型： 外文期刊

第一作者： Shu, J. T.

作者： Shu, J. T.;Bao, W. B.;Zhang, H. X.;Chen, G. H.;Shu, J. T.;Zhang, X. Y.

作者机构：

关键词： Chicken;Inosine monophosphate content;Meat quality;purH gene;Single nucleotide polymorphism

期刊名称：ANIMAL BIOTECHNOLOGY （ 影响因子：2.282； 五年影响因子：1.702 ）

ISSN： 1049-5398

年卷期： 2008 年 19 卷 4 期

页码：

收录情况： SCI

摘要： The current study was designed to investigate the effects of the purH gene on chicken muscle inosine monophosphate (IMP) content. Muscle IMP content was measured in five chicken breeds. Single nucleotide polymorphisms (SNPs) were detected by PCR-SSCP and DNA sequencing. Two SNPs were detected, A/T substitution at position 8023 in exon 9, and T/C substitution at position 17446 in exon 16. The results indicated that only T17446C polymorphism was associated with IMP content. The haplotype effect was higher than the single genotype effect. We tentatively conclude that purH gene is a candidate locus or linked to a major gene that affects muscle IMP content. Haplotypes are superior to single genotypes as potential molecular markers for meat quality traits in chicken.

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