Synthesis and biological activities of 1,2,3-thiadiazol-4-acetamide (Acetmorpholide) derivatives

文献类型： 外文期刊

第一作者： Dong Wei-Li

作者： Dong Wei-Li;Yao Hong-Wei;Wang Feng-Long;Li Zheng-Ming;Shen Li-Li;Qian Yu-Mei;Zhao Wei-Guang

作者机构：

关键词： 1,2,3-thiadiazole;acetamide;biological activity

期刊名称：CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE （ 影响因子：0.65； 五年影响因子：0.481 ）

ISSN： 0251-0790

年卷期： 2007 年 28 卷 9 期

页码：

收录情况： SCI

摘要： In the investigation of new agrochemicals, we found 1,2,3-thiadiazole derivatives with good biological activities, had received only limited attention, but commercial pesticides containing I 2,3-thiadiazole often possess a unique active mechanism, such as TDZ, BTH and tiadinil. We became interested in making 1, 2,3-thiadiazoleacetamides, analogues of three commercial pesticides. In order to search for novel 1 2,3-thiadiazole derivatives with high activities, we designed and synthesized a series of novel 1 2,3-thiadiazole-4-acetamide (acetmorpholide) derivatives. using diketene as the starting materials. Their structures were identified by means of elemental analysis, IR, H-1 NMR and MS spectra. The results of the preliminary biological activity tests show that some of the compounds exhibit a better anti-TMV activity, plant growth, regulator activity and fungicidal activity.

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