Long terminal repeat sequences from virulent and attenuated equine infectious anemia virus demonstrate distinct promoter activities

文献类型： 外文期刊

第一作者： Zhou, Tao

作者： Zhou, Tao;Yuan, Xiu-Fang;Hou, Shao-Hua;Tu, Ya-Bin;Peng, Jin-Mei;Wen, Han-Xin;Qiu, Hua-H;Wu, Dong-Lai;Chen, Huan-Chun;Wang, Xiao-Jun;Tong, Guang-Zhi

作者机构：

关键词： EIAV attenuation;LTR variation;In vivo;In vitro;MDM;promoter activity

期刊名称：VIRUS RESEARCH （ 影响因子：3.303； 五年影响因子：3.445 ）

ISSN： 0168-1702

年卷期： 2007 年 128 卷 1-2 期

页码：

收录情况： SCI

摘要： In the early 1970s, the Chinese Equine Infectious Anemia Virus (EIAV) vaccine, EIAV(DLA), was developed through successive passages of a wild-type virulent virus (EIAV(L)) in donkeys in vivo and then in donkey macrophages in vitro. EIAV attenuation and cell tropism adaptation are associated with changes in both envelope and long terminal repeat (LTR). However, specific LTR changes during Chinese EIAV attenuation have not been demonstrated. In this study, we compared LTR sequences from both virulent and attenuated EIAV strains and documented the diversities of LTR sequence from in vivo and in vitro infections. We found that EIAV LTRs of virulent strains were homologous, while EIAV vaccine have variable LTRs. Interestingly, experimental inoculation of EIAV(DLA) into a horse resulted in a restriction of the LTR variation, Furthermore, LTRs from EIAVDLA showed higher Tat transactivated activity than LTRs from virulent strains. By using chimeric clones of wild-type LTR and vaccine LTR, the main difference of activity was mapped to the changes of R region, rather than U3 region. (C) 2007 Elsevier B.V. All rights reserved.

分类号：

  • 相关文献

[1]Carbon adaptation influence the antagonistic ability of Pseudomonas aeruginosa against Fusarium oxysporum f. sp melonis. Wang, Yanli,Sun, Guochang,Li, Bin,Tang, Qiaomei,Chen, Xiaoling,Xie, Guanlin,Li, Hongye,Yu, Rongrong,Wu, Zhiyi. 2011

[2]In vitro and in vivo antioxidative and radioprotective capacities of polysaccharide isolated from Mesona Blumes gum. Feng, Tao,Sang, Min,Zhuang, Haining,Xu, Zhimin,Zhuang, Haining,Xu, Zhimin. 2017

[3]Porcine Mx1 fused to HIV Tat protein transduction domain (PTD) inhibits classical swine fever virus infection in vitro and in vivo. Jing, Jiao,Shi, Baojun,Xu, Qianqian,Zhou, Bin,Chen, Puyan,Li, Wenliang,Liu, Ke,Ma, Zhiyong. 2015

[4]Angiotensin I Converting Enzyme (ACE) inhibitory activity and antihypertensive effects of grass carp peptides. Wang Shen,Lin Li-mei,Wu Yong-ning,Fang Min,Yu Ya-qin,Zhou Jia,Gong Zhi-yong,Wu Yong-ning. 2014

[5]Enhanced transgene expression in rice following selection controlled by weak promoters. Zhou, Jie,Yang, Yong,Wang, Xuming,Yu, Feibo,Yu, Chulang,Chen, Juan,Cheng, Ye,Yan, Chenqi,Chen, Jianping. 2013

[6]Construction of a lentiviral T/A vector for direct analysis of PCR-amplified promoters. Yu, Fu-xian,Zhu, Zhi-wei,Chen, Xiao-yu,Huang, Jing,Shi, Tuan-yuan,Li, Jun-xing,Pan, Jian-zhi.

[7]Cloning and characterization of two duplicated interleukin-17A/F2 genes in common carp (Cyprinus carpio L.): Transcripts expression and bioactivity of recombinant IL-17A/F2. Li, Hongxia,Yu, Juhua,Li, Jianlin,Tang, Yongkai,Yu, Fan,Yu, Juhua,Zhou, Jie,Yu, Wenjuan.

[8]Gene Expression of Type VI Secretion System Associated with Environmental Survival in Acidovorax avenae subsp avenae by Principle Component Analysis. Cui, Zhouqi,Li, Bin,Kakar, Kaleem Ullah,Ojaghian, Mohammad Reza,Xie, Guanlin,Jin, Guoqiang,Wang, Yangli,Sun, Guochang. 2015

[9]Erythromycin Resistance of Streptococcus suis Isolates In Vivo. Jiang Cheng-gang,Cai Xue-hui,Qiu Hua-ji,Li Yan-hua,Tong Heng-min,Liu Di-qiu,Lei Lian-cheng,Sun Chang-jiang. 2009

[10]Innate Immune Responses in ALV-J Infected Chicks and Chickens with Hemangioma In Vivo. Feng, Min,Xie, Tingting,Li, Zhenhui,Zhang, Xiquan,Feng, Min,Xie, Tingting,Li, Zhenhui,Zhang, Xiquan,Feng, Min,Xie, Tingting,Li, Zhenhui,Zhang, Xiquan,Dai, Manman,Shi, Meiqing. 2016

[11]Transparent Tiger barb Puntius tetrazona, a fish model for in vivo analysis of nocardial infection. Wang, F.,Liv, C.,Chang, O. Q.,Feng, Y. Y.,Jiang, L.,Li, K. B.,Wang, X. G.. 2017

[12]In-Field, In Situ, and In Vivo 3-Dimensional Elemental Mapping for Plant Tissue and Soil Analysis Using Laser-Induced Breakdown Spectroscopy. Zhao, Chunjiang,Dong, Daming,Du, Xiaofan,Zheng, Wengang. 2016

[13]Comprehensive Analysis of Tiamulin Metabolites in Various Species of Farm Animals Using Ultra-High-Performance Liquid Chromatography Coupled to Quadrupole/Time-of-Flight. Sun, Feifei,Zhang, Huiyan,Wang, Zhanhui,Shen, Jianzhong,Zhang, Suxia,Cao, Xingyuan,Sun, Feifei,Zhang, Huiyan,Wang, Zhanhui,Shen, Jianzhong,Zhang, Suxia,Cao, Xingyuan,Yang, Shupeng,Zhou, Jinhui,Li, Yi,Zhang, Jinzhen,Jin, Yue,Yang, Shupeng,Zhou, Jinhui,Li, Yi,Zhang, Jinzhen,Jin, Yue,Li, Yanshen.

[14]ZIP restores estrogen receptor expression and response to Tamoxifen in estrogen receptor negative tumors. Zhu, Ning,Miao, Ruidong,Du, Yuping,Yang, Jinbo,Zhang, Jing,Qin, Xiaodong.

[15]Sulforaphane reduces vascular inflammation in mice and prevents TNF-alpha-induced monocyte adhesion to primary endothelial cells through interfering with the NF-kappa B pathway. Nallasamy, Palanisamy,Brooke, Elizabeth A. S.,Shah, Halley,Jia, Zhenquan,Si, Hongwei,Babu, Pon Velayutham Anandh,Pan, Dengke,Fu, Yu,Zhen, Wei,Liu, Dongmin,Fu, Yu,Zhen, Wei,Zhu, Hong,Li, Yunbo.

[16]Identification of in vivo protein phosphorylation sites in human pathogen Schistosoma japonicum by a phosphoproteomic approach. Luo, Rong,Zhou, Chunjing,Lin, Jiaojiao,Yang, Dehao,Shi, Yaojun,Cheng, Guofeng.

[17]Ovulation, fertilization and preimplantation embryonic development in raccoon dogs (Nyctereutes procyonoides). Xu, Baozeng,Xu, Baozeng,Feng, Huai L..

[18]Microsensor in vivo monitoring of oxidative burst in oilseed rape (Brassica napus L.) leaves infected by Sclerotinia sclerotiorum. Xu, Qiao,Liu, Sheng-Yi,Guo, Xue-Lan,Dong, Xu-Yan,Li, Pei-Wu,Chen, Hong,Xu, Qiao,Zou, Qiu-Ju,Zhao, Yuan-Di,Xu, Qiao,Zou, Qiu-Ju,Zhao, Yuan-Di,Song, Dan-Yang,Chen, Hong.

[19]Membrane protein profiling of Acidovorax avenae subsp avenae under various growth conditions. Li, Bin,Wang, Li,Ge, Mengyu,Wang, Yanli,Sun, Guochang,Ibrahim, Muhammad,Mannan, Shazia,Asif, Muhammad.

[20]In vitro organogenesis and plant regeneration from leaves of Actinidia eriantha Benth. cv White (kiwifruit). Wu, Y. J.,Xie, M.,Long, Q. J.. 2011

作者其他论文 更多>>

微信小程序