Modulation of immune function by conjugated linoleic acid in chickens

文献类型： 外文期刊

第一作者： He, Xi

作者： He, Xi;Zhang, Shirui;Zhang, Haijun;Yang, Xiaojun;Xiao, Wenjun;Ren, Guopu

作者机构：

关键词： conjugated linoleic acid;chickens;immune function;prostaglandin E2;fatty acids composition

期刊名称：FOOD AND AGRICULTURAL IMMUNOLOGY （ 影响因子：3.101； 五年影响因子：2.573 ）

ISSN： 0954-0105

年卷期： 2007 年 18 卷 3-4 期

页码：

收录情况： SCI

摘要： This study was carried out to determine the effects of dietary supplementation with conjugated linoleic acid (CLA) on the immune response and fatty acid composition of the spleen in chickens. Three hundred male broiler chicks were randomly allotted into five dietary treatments with different inclusion levels of CLA (0, 5.0, 10.0, 15.0, 20.0 g pure CLA/kg). The relative weights of the thymus and bursa were significantly increased (p < 0.05) in chickens fed 5.0 or 10.0 g CLA/kg diet compared with control chickens at age 21 days. Peripheral blood mononuclear cell (PBMC) proliferation and anti-NDV titers were enhanced in 10.0 g CLA/kg dietary treatments (p < 0.05). CLA diets resulted in lower PGE(2) synthesis than the control diet (p < 0.05). Dietary CLA readily incorporated into the phospholipids of immune tissues and altered the fatty acid composition of the spleen with increased LO (n-3) and decreased LA, AA (n-6) relative amounts in chicks. Negative correlation was observed between PGE(2) synthesis and lymphocyte proliferation at age 21 days (R(2)= - 0.677, p < 0.05), but no correlation between PGE(2) synthesis and anti-NDV titres was observed. The results indicated that dietary CLA could enhance the immune response in chicks, which might be due to changes of eicosanoid production. However, the PGE(2)-mediated effects cannot be accounted for solely by the overall effect of CLA on immune function.

分类号：

  • 相关文献

[1]Comparisons of proximate compositions, fatty acids profile and micronutrients between fiber and oil flaxseeds (Linum usitatissimum L.). Zou, Xian-Guo,Chen, Xiao-Lu,Hu, Jiang-Ning,Zhu, Xue-Mei,Deng, Ze-Yuan,Wang, Yu-Fu,Gong, De-Ming.

[2]Relationship between proteome changes of Longissimus muscle and intramuscular fat content in finishing pigs fed conjugated linoleic acid. Zhong, Weijing,Jiang, Zongyong,Zheng, Chuntian,Lin, Yingcai,Zhong, Weijing,Yang, Lin,Zou, Shutong. 2011

[3]Effectiveness of Oils Rich in Linoleic and Linolenic Acids to Enhance Conjugated Linoleic Acid in Milk from Dairy Cows. Bu, D. P.,Wang, J. Q.,Dhiman, T. R.,Liu, S. J..

[4]PRODUCTION OF CONJUGATED LINOLEIC ACID BY WHOLE-CELL OF LACTOBACILLUS PLANTARUM A6-1F. Zhao, Hong-wei,Lv, Jia-ping,Li, Shu-rong. 2011

[5]Lipase-catalyzed acylation of l-carnitine with conjugated linoleic acid in [Bmim]PF6 ionic liquid. Tian, Jinqiang,Wang, Qiang,Tian, Jinqiang,Wang, Qiang,Zhang, Zhongyuan. 2009

[6]Effects of garlic oil on milk fatty acid profile and lipogenesis-related gene expression in mammary gland of dairy goats. Zhu, Zhi,Hang, Suqin,Zhu, Honglong,Mao, Shengyong,Zhu, Weiyun,Zhong, Sheng. 2013

[7]Effects of trans-10, cis-12-conjugated linoleic acid on mice are influenced by the dietary fat content and the degree of murine obesity. Li, Shi-Li,Li, Mei-Juan,Gou, Ke-Mian,Ma, Shu-Yu,Fan, Zhi-Ying,Xu, Bin-Rui,Cao, Wen-Guang.

[8]Production of conjugated linoleic acid by Propionibacterium freudenreichii. Wang, Li-Min,Lv, Jia-Ping,Chu, Zhong-Qiu,Cui, Yuan-Yuan,Ren, Xing-Huan. 2007

[9]The effect of steam-flaked and extruded full-fat soybeans on the concentration of conjugated linoleic acid in the milk fat of dairy cows. Li, Yanling,Meng, Qingxiang,Li, Yanling,Diao, Qiyu. 2009

[10]Effect of dietary conjugated linoleic acid (CLA) on the growth and lipid metabolism of geese and fatty acid composition of their tissues. Zhang, Xu-hui,Wang, Bao-wei,Wang, Lei,Long, Fang-yu,Yang, Zhi-gang,Yu, Shi-hao,Wang, Ya-chao,Wei, Xiao-xiao,Jing, Li-zhen,Liu, Guang-lei. 2008

[11]Impact of region on the composition of milk fatty acids in China. Yang, Yongxin,Wang, Jiaqi,Yuan, Tingjie,Bu, Dengpan,Yang, Jinhui,Zhou, Lingyun,Sun, Peng,Zhang, Juanxia,Yang, Yongxin. 2013

[12]Effects of dietary conjugated linoleic acids on lipid metabolism and antioxidant capacity in laying hens. Qi, Xiaolong,Wu, Shugeng,Zhang, Haijun,Yue, Hongyuan,Xu, Shaohui,Ji, Feng,Qi, Guanghai.

[13]Effects of different corn silage: Alfalfa silage ratios and full fat extruded soybeans on milk composition, conjugated linoleic acids content in milk fat and performance of dairy cows. Yan, Rong,Han, Jian-guo,Li, Zhiqiang,Yuzhu,Zhang, Xian. 2010

[14]Influence of fish/soybean oil supplementation on milk conjugated linoleic acid and mammary gland SCD gene expression in dairy cows. Bu, D. P.,Wang, J. Q.,Dhiman, T. R.,Liu, S. J.. 2007

[15]Effectiveness of linoleic and linolenic acid for enhancing conjugated linoleic acid in milk from dairy cows.. Dhiman, T. R.,Shijun, L.. 2006

[16]Seroprevalence of Chlamydophila infection in chickens, ducks, geese and pigeons in Southern China. Zhang, Y. B.,Lin, R. Q.,Wang, X. Q.,Yan, C.,Xu, M. J.,Zhu, X. Q.,Lin, R. Q.,Wang, X. Q.,He, X. H.,Cheng, T.,Wang, Y. N.,Yuan, Z. G.,Yan, C.,Zhu, X. Q.,Zhu, X. Q.. 2011

[17]Immunoprotection induced by CpG-ODN/Poly(I:C) combined with recombinant gp90 protein in chickens against reticuloendotheliosis virus infection. Yuan, Fei,Chu, Ying,Li, Hongmei,Sun, Shuhong,Zhao, Peng,Chang, Shuang,Guo, Huijun,Qi, Lihong. 2017

[18]Effects of caponization and ovariectomy on objective indices related to meat quality in chickens. Wen, J..

[19]Effects of aluminum chloride on serum proteins, bilirubin, and hepatic trace elements in chickens. Wang, Ben,Zhang, Hongling,Liu, Liming,Li, Guojiang,Song, Yongli,Zhu, Yanzhu,Li, Yanfei.

[20]Effects of diclazuril on apoptosis and mitochondrial transmembrane potential in second-generation merozoites of Eimeria tenella. Zhou, Bianhua,Xue, Feiqun,Wang, Xiaoyang,Fei, Chenzhong,Wang, Mi,Zhang, Tao,Yao, Xiujuan,He, Peiyi,Wang, Hongwei.

作者其他论文 更多>>

微信小程序