Complex Virus-Host Interactions Involved in the Regulation of Classical Swine Fever Virus Replication: A Minireview

文献类型: 外文期刊

第一作者: Li, Su

作者: Li, Su;Wang, Jinghan;Yang, Qian;Anwar, Muhammad Naveed;Yu, Shaoxiong;Qiu, Hua-Ji

作者机构:

关键词: classical swine fever virus;virus-cell interactions;attachment;entry;cell apoptosis;virus life cycle

期刊名称:VIRUSES-BASEL ( 影响因子:5.048; 五年影响因子:5.127 )

ISSN: 1999-4915

年卷期: 2017 年 9 卷 7 期

页码:

收录情况: SCI

摘要: Classical swine fever (CSF), caused by classical swine fever virus (CSFV), is one of the most devastating epizootic diseases of pigs in many countries. Viruses are small intracellular parasites and thus rely on the cellular factors for replication. Fundamental aspects of CSFV-host interactions have been well described, such as factors contributing to viral attachment, modulation of genomic replication and translation, antagonism of innate immunity, and inhibition of cell apoptosis. However, those host factors that participate in the viral entry, assembly, and release largely remain to be elucidated. In this review, we summarize recent progress in the virus-host interactions involved in the life cycle of CSFV and analyze the potential mechanisms of viral entry, assembly, and release. We conclude with future perspectives and highlight areas that require further understanding.

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