文献类型： 外文期刊

第一作者： Ding, EY

作者： Ding, EY;Xiang, WH

作者机构：

期刊名称：VIRAL IMMUNOLOGY （ 影响因子：2.257； 五年影响因子：1.882 ）

ISSN： 0882-8245

年卷期： 1997 年 10 卷 2 期

页码：

收录情况： SCI

摘要： In this study, goats were experimentally infected with caprine arthritis-encephalitis virus (CAEV). Anti-CAEV antibodies were detected in vivo using indirect enzyme-linked immunosorbent assay (ELISA) and Western blot assays. The results showed that the sensitivity of detection of anti-CAEV antibodies using indirect ELISA was relatively high, whereas Western blotting was very sensitive for detection of P28 anti-CAEV antibody as 4 days postinfection. Apparently, because of high immunogenicity of P28 antigen, the detection of antibodies specific for this viral protein may represent a valuable assay to detect early infection. CAEV related to other lentiviruses may be useful in studies of human immunodeficiency virus (HIV) and related viruses in animal models.

分类号：