Roles of LncRNAs in Viral Infections

文献类型: 外文期刊

第一作者: Liu, Weiwei

作者: Liu, Weiwei;Ding, Chan

作者机构:

关键词: long non-coding RNAs;virus infection;cellular lncRNAs;virus-encoded lncRNAs;cell-virus interaction

期刊名称:FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY ( 影响因子:5.293; 五年影响因子:5.882 )

ISSN: 2235-2988

年卷期: 2017 年 7 卷

页码:

收录情况: SCI

摘要: Many proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 nucleotides in length, have been recently described as critical regulators in viral infections. Accumulating research indicates that lncRNAs are important in the development and progression of infectious diseases. LncRNAs are not only involved in anti-viral responses, but in many different virus-host interactions, some of which may be beneficial to the virus. Here we review the current knowledge regarding host and viral lncRNAs and their roles in viral infections. In addition, the potential of using lncRNAs as diagnostic biomarkers is discussed.

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