Characterisation of newly emerged isolates of classical swine fever virus in China, 2014-2015

文献类型: 外文期刊

第一作者: Leng, Chaoliang

作者: Leng, Chaoliang;Kan, Yunchao;Yao, Lunguang;Li, Mingliang;Zhai, Hongyue;Shi, Hongfei;Ji, Jun;Qiu, Reng;Zhang, Hongliang;Li, Zhen;Liu, Chunxiao;Tian, Zhijun

作者机构:

关键词: swine;classical swine fever virus;evolution;subgenotype 2.1d;China

期刊名称:JOURNAL OF VETERINARY RESEARCH ( 影响因子:1.744; 五年影响因子:1.838 )

ISSN: 2450-7393

年卷期: 2017 年 61 卷 1 期

页码:

收录情况: SCI

摘要: Introduction: In 2014-2015, the epidemic of classical swine fever (CSF) occurred in many large-scale pig farms in different provinces of China, and a subgenotype 2.1d of CSF virus (CSFV) was newly identified. Material and Methods: The phylogenetic relationship, genetic diversity, and epidemic status of the 2014-2015 CSFV isolates, 18 new CSFV isolates collected in 2015, and 43 other strains isolated in 2014-2015 were fully analysed, together with 163 CSFV reference isolates. Results: Fifty-two 2014-2015 isolates belonged to subgenotype 2.1d and nine other isolates belonged to subgenotype 2.1b. The two subgenotype isolates showed unique molecular characteristics. Furthermore, the 2.1d isolates were found to possibly diverge from 2.1b isolates. Conclusion: This study suggests that the Chinese CSFVs will remain pandemic.

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