Punctaporonins N-S, New Caryophyllene Sesquiterpenoids from Cytospora sp.

文献类型: 外文期刊

第一作者: Li, Yan

作者: Li, Yan;Wang, Qingbin;Che, Yongsheng;Li, Yan;Liu, Xingzhong

作者机构:

期刊名称:BIOMED RESEARCH INTERNATIONAL ( 影响因子:3.411; 五年影响因子:3.62 )

ISSN: 2314-6133

年卷期: 2017 年

页码:

收录情况: SCI

摘要: Six new caryophyllene sesquiterpenoids, punctaporonins N-S (1-6), and three known ones, 6-hydroxypunctaporonins B (7), A (8), and E (9), have been isolated from solid cultures of Cytospora sp. The structures of 1-6 were elucidated primarily by NMR spectroscopy. The absolute configuration of 1 was assigned by X-ray crystallographic analysis of its. S-MTPA ester. Compounds 2, 5, and 6 showed modest cytotoxicity against HeLa cells.

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