The first whole genome sequence and pathogenicity characterization of a fowl adenovirus 4 isolated from ducks associated with inclusion body hepatitis and hydropericardium syndrome

文献类型： 外文期刊

第一作者： Pan, Qing

作者： Pan, Qing;Liu, Linlin;Wang, Yongqiang;Zhang, Yanping;Qi, Xiaole;Liu, Changjun;Gao, Yulong;Wang, Xiaomei;Cui, Hongyu;Wang, Xiaomei

作者机构：

关键词： FAdV-4;ducks;whole genome sequence;novel genotype;hypervirulent

期刊名称：AVIAN PATHOLOGY （ 影响因子：3.378； 五年影响因子：3.237 ）

ISSN： 0307-9457

年卷期： 2017 年 46 卷 5 期

页码：

收录情况： SCI

摘要： In June 2015, an infectious disease with high prevalence causing severe hydropericardium syndrome (HPS) first appeared in duck farms of northeast China. The disease showed high morbidity of 35% and mortality of 15% in a commercial duck farm with 200,000 45-day-old ducks. One strain of hypervirulent fowl adenovirus serotype 4 was identified and designated as HLJDAd15. The whole genome of the duck isolate was sequenced and found to contain the same large deletions as a genotype that has become prevalent in chickens in China recently, indicating that this disease might be transmitted from chickens to ducks. The pathogenicity of HLJDAd15 was evaluated in SPF chickens and ducks. The results showed that chickens were more susceptible to this new genotype of fowl adenovirus, and it was more difficult to infect ducks than chickens with the duck origin virus. Thus, it appears that this severe HPS in ducks is far more likely to have been transmitted from chickens to ducks than from ducks to ducks. Therefore, transmission from chickens to ducks constitutes a threat to the duck farming industry, and this transmission route is a very important consideration for the prevention and control of the new genotype of fowl adenovirus. This is the first whole genome sequence of a FAdV-4 isolated from ducks, and this information is important for understanding the molecular characteristics and evolution of aviadenoviruses. The potential risks of infection with this new hypervirulent FAdV-4 genotype in chickens and ducks urgently require an effective vaccine.

分类号：

  • 相关文献

[1]Characterization of a hypervirulent fowl adenovirus 4 with the novel genotype newly prevalent in China and establishment of reproduction infection model of hydropericardium syndrome in chickens. Pan, Q.,Liu, L.,Gao, Y.,Liu, C.,Qi, X.,Zhang, Y.,Wang, Y.,Li, K.,Gao, L.,Wang, X.,Cui, H.,Wang, X..

[2]Genome-wide analysis of the RING finger gene family in apple. Li, Yanze,Wu, Bingjiang,Yang, Guodong,Wu, Changai,Zheng, Chengchao,Yu, Yanli.

[3]An Inactivated Novel Genotype Fowl Adenovirus 4 Protects Chickens against the Hydropericardium Syndrome That Recently Emerged in China. Pan, Qing,Yang, Yanchao,Gao, Yulong,Qi, Xiaole,Liu, Changjun,Zhang, Yanping,Cui, Hongyu,Wang, Xiaomei,Wang, Xiaomei. 2017

[4]Fowl adenovirus serotype 4: Epidemiology, pathogenesis, diagnostic detection, and vaccine strategies. Li, P. H.,Zheng, P. P.,Zhang, T. F.,Wen, G. Y.,Shao, H. B.,Luo, Q. P.,Li, P. H.,Zheng, P. P.,Zhang, T. F.,Wen, G. Y.,Shao, H. B.,Luo, Q. P..

[5]Interactions of dietary protein and threonine on growth performance in Pekin ducklings from 1 to 14 days of age. Jiang, Y.,Xie, M.,Tang, J.,Hou, S. S.,Jiang, Y.,Tang, J.,Qiao, S. Y.,Wen, Z. G.,Zhu, Y. W.. 2018

[6]Seroprevalence of Chlamydophila infection in chickens, ducks, geese and pigeons in Southern China. Zhang, Y. B.,Lin, R. Q.,Wang, X. Q.,Yan, C.,Xu, M. J.,Zhu, X. Q.,Lin, R. Q.,Wang, X. Q.,He, X. H.,Cheng, T.,Wang, Y. N.,Yuan, Z. G.,Yan, C.,Zhu, X. Q.,Zhu, X. Q.. 2011

[7]Nutritional requirements of meat-type and egg-type ducks: what do we know?. Fouad, Ahmed Mohamed,Ruan, Dong,Wang, Shuang,Chen, Wei,Xia, Weiguang,Zheng, Chuntian,Fouad, Ahmed Mohamed. 2018

[8]Effects of riboflavin supplementation on growth performance, carcass traits, and riboflavin status of growing male white Pekin ducks. Tang, J.,Hu, J.,Wen, Z. G.,Jiang, Y.,Huang, W.,Xie, M.,Hou, S. S.,Tang, J.,Wen, Z. G.,Jiang, Y.,Guo, Y. M.,AL-Kateb, H..

[9]Unique sequence characteristics of genes in the leftmost region of unique long region in duck enteritis virus. Liu, Xiaoli,Liu, Shengwang,Li, Huixin,Han, Zongxi,Shao, Yuhao,Kong, Xiangang.

[10]Effects of dietary protein on threonine requirements of Pekin ducks from hatch to 21 days of age. Jiang, Y.,Uzma, M.,Tang, T.,Hou, S. S.,Huang, W.,Xie, M.,Jiang, Y.,Tang, T.,Wen, Z. G..

[11]Hypothalamic protein profiles associated with inhibited feed intake of ducks fed with insufficient dietary arginine. Wang, C.,Xie, M.,Huang, W.,Xie, J. J.,Hou, S. S.,Wang, C.,Zheng, A. J..

[12]Effect of feed consumption levels on growth performance and carcass composition during the force-feeding period in foie gras production of male Mule ducks. Wen, Z. G.,Jiang, Y.,Tang, J.,Xie, M.,Hou, S. S.,Wen, Z. G.,Yang, P. L.,Jiang, Y.,Tang, J..

[13]Effects of low-protein diets on growth performance and carcass yield of growing White Pekin ducks. Xie, M.,Jiang, Y.,Tang, J.,Zhang, Q.,Huang, W.,Hou, S. S.,Wen, Z. G..

[14]Effects of niacin status on tryptophan requirements of starter white Pekin ducks. Xie, M.,Huang, W.,Hon, S. S.,Han, X. F.. 2014

[15]Effects of excess DL- and L-methionine on growth performance of starter Pekin ducks. Xue, J. J.,Xie, M.,Tang, J.,Huang, W.,Zhang, Q.,Hou, S. S.. 2018

[16]The quest of influenza A viruses for new hosts. Liu, M,Guan, Y,Peiris, M,He, S,Webby, RJ,Perez, D,Webster, RG. 2003

[17]Effects of alfalfa meal on the intestinal microbial diversity and immunity of growing ducks. Jiang, J. F.,Song, X. M.,Wu, J. L.,Jiang, Y. Q..

[18]Protective efficacy in chickens, geese and ducks of an H5N1-inactivated vaccine developed by reverse genetics. Tian, GB,Zhang, SH,Li, YB,Bu, ZG,Liu, PH,Zhou, JP,Li, CJ,Shi, JZ,Yu, KZ,Chen, HL. 2005

[19]Apoptosis Induced by Duck Reovirus p10.8 Protein in Primary Duck Embryonated Fibroblast and Vero E6 Cells. Geng, Hongwei,Zhang, Yun,Guo, Dongchun,Wang, Yu,Liu, Ming,Zhang, Yun,Liu-Partanen, Yin,Tong, Guangzhi.

作者其他论文 更多>>

微信小程序