文献类型： 外文期刊
第一作者： Liu, Chen
作者： Liu, Chen;Liu, Chen;Jin, Jing;Rietjens, Ivonne M. C. M.
作者机构：
关键词： New approach methodologies (NAMs); Gut microbiota; Microbiome- host interaction; Quantitative in vitro to in vivo extrapolation (QIVIVE); Physiologically based kinetic (PBK) model; Gut-on-a-chip
期刊名称：CURRENT OPINION IN TOXICOLOGY （ 影响因子：4.6； ）
ISSN： 2468-2020
年卷期： 2023 年 35 卷
页码：
收录情况： SCI
摘要： Gut microbiota plays an important role in host health and disand other xenobiotics, while these chemicals and their metabolites can also modulate the gut microbiota. The present review provided an overview of the state-of-the-art in the application of in vitro and in silico based new approach methodologies (NAMs) to study these microbiome-host interactions in a non-invasive way and without the need for the use of animal or human studies.
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