Chromosome-level genome assembly of Guide Black-Fur sheep (Ovis aries)

文献类型： 外文期刊

第一作者： Lu, Zengkui

作者： Lu, Zengkui;Yuan, Chao;An, Xuejiao;Guo, Tingting;Liu, Jianbin;Lu, Zengkui;Yuan, Chao;An, Xuejiao;Guo, Tingting;Liu, Jianbin;Chen, Zhixiang

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期刊名称：SCIENTIFIC DATA （ 影响因子：5.8； 五年影响因子：8.9 ）

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年卷期： 2024 年 11 卷 1 期

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收录情况： SCI

摘要： Guide Black-Fur sheep (GD) is a breed of Tibetan sheep (Ovis aries) that lives in the Qinghai-Tibetan plateau region at an altitude of over 4,000 m. However, a lack of genomic information has made it difficult to understand the high-altitude adaptation of these sheep. We sequenced and assembled the GD reference genome using PacBio, Hi-C, and Illumina sequencing technologies. The final assembled genome size was 2.73 Gb, with a contig N50 of 20.30 Mb and a scaffold N50 of 107.63 Mb. The genome is predicted to contain 20,759 protein-coding genes, of which 98.42 have functional annotations. Repeat elements account for approximately 52.2% of the genomic landscape. The completeness of the GD genome assembly is highlighted by a BUSCO score of 93.1%. This high-quality genome assembly provides a critical resource for future molecular breeding and genetic improvement of Tibetan sheep.

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