GABA-Decorated Nanocarrier for Smart Delivery of Fludioxonil for Targeted Control of Banana Wilt Disease
文献类型： 外文期刊
第一作者： He, Liangheng
作者： He, Liangheng;Xiao, Chunxia;Zhu, Li;Deng, Wenjie;Zhang, Yanheng;Wu, Xinzhou;Xu, Hanhong;Jia, Jinliang;He, Liangheng;Zhu, Li;Deng, Wenjie;Zhang, Yanheng;Li, Yang;Jia, Jinliang;Wu, Hanxiang
作者机构：
关键词： gamma-aminobutyric acid; targeted; nanocarrier; fludioxonil; banana wilt disease
期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：6.2； 五年影响因子：6.4 ）
ISSN： 0021-8561
年卷期： 2024 年 72 卷 48 期
页码：
收录情况： SCI
摘要： Developing a targeted nanopesticide to control the vascular disease of banana in agriculture is crucial to improve pesticide utilization. In this study, according to the degree of functionalization, three gamma-aminobutyric acid (GABA)-decorated nanocarriers (PSI-GABA(8), PSI-GABA(18), and PSI-GABA(28)) were constructed for smart delivery of nonsystemic fungicide in banana phloem tissues. Fludioxonil (Flu) was loaded in nanocarriers to form Flu@PSI-GABA nanoparticles with a core/shell structure for control of banana wilt disease. Results demonstrated that the delivery dosage of Flu was up to 1.6 mg/L in castor phloem sap using PSI-GABA(28) nanocarriers. In vitro results showed that the EC50 of Flu@PSI-GABA(28) was 0.0116 mg/L, and the inhibitory activity was about 8.8 times higher than that of technical-grade (TC) Flu. Flu@PSI-GABA(28) could be transported for long distances and accumulated to the rhizome of banana by foliar application, and the control effectiveness was about 20 times that of the conventional Flu (50% WP) for the banana wilt. This study provides a distinctive guidance for effective control of vascular diseases in precision agriculture application.
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