Research Note: Association of single nucleotide polymorphism of AKT3 with egg production traits in White Muscovy ducks (Cairina moschata)

文献类型： 外文期刊

第一作者： Bello, Semiu Folaniyi

作者： Bello, Semiu Folaniyi;Xu, Haiping;Li, Kan;Guo, Lijin;Zhang, Siyu;Bekele, Endashaw Jebessa;Zheng, Ming;Xian, Mingjian;Abdalla, Bahareldin Ali;Zhang, Dexiang;Zhang, Xiquan;Nie, Qinghua;Bello, Semiu Folaniyi;Xu, Haiping;Li, Kan;Guo, Lijin;Zhang, Siyu;Bekele, Endashaw Jebessa;Zheng, Ming;Xian, Mingjian;Abdalla, Bahareldin Ali;Zhang, Dexiang;Zhang, Xiquan;Nie, Qinghua;Bello, Semiu Folaniyi;Xu, Haiping;Li, Kan;Guo, Lijin;Zhang, Siyu;Bekele, Endashaw Jebessa;Zheng, Ming;Xian, Mingjian;Abdalla, Bahareldin Ali;Zhang, Dexiang;Zhang, Xiquan;Nie, Qinghua;Ahmed, Ridwan Olawale;Adeola, Adeniyi Charles;Adetula, Adeyinka Abiola;Lawal, Raman Akinyanju;Zhu, Weijian;Zhang, Dexiang;Ji, Congliang;Nie, Qinghua

作者机构：

关键词： AKT3; mRNA expression; egg production traits; variation

期刊名称：POULTRY SCIENCE （ 影响因子：4.4； 五年影响因子：4.4 ）

ISSN： 0032-5791

年卷期： 2022 年 101 卷 12 期

页码：

收录情况： SCI

摘要： Prior studies on transcriptomes of hypothalamus and ovary revealed that AKT3 is one of the candidate genes that might affect egg production in White Muscovy ducks. The role of AKT3 in the uterus during reproductive processes cannot be overemphasized. However, functional role of this gene in the tissues and on egg production traits of Muscovy ducks remains unknown. To identify the relationship between AKT3 and egg production traits in ducks, relative expression profile was first examined prior to identifying the variants within AKT3 that may underscore egg production traits [age at first egg (AFE), number of eggs at 300 d (N300D), and number of eggs at 59 wk (N59W)] in 549 ducks. The mRNA expression of AKT3 gene in high producing (HP) ducks was significantly higher than low producing (LP) ducks in the ovary, oviduct, and hypothalamus (P < 0.05 or 0.001). Three variants in AKT3 (C-3631A, C-3766T, and C-3953T) and high linkage block between C-3766T and C-3953T which are significantly (P < 0.05) associated with N300D and N59W were discovered. This study elucidates novel knowledge on the molecular mechanism of AKT3 that might be regulating egg production traits in Muscovy ducks.

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