Changes in Blood Metabolic Profiles Reveal the Dietary Deficiencies of Specific Nutrients and Physiological Status of Grazing Yaks during the Cold Season in Qinghai Province of China

文献类型： 外文期刊

第一作者： Gao, Jian

作者： Gao, Jian;Sun, Zhanying;Cheng, Yanfen;Yang, Deyu;Niu, Jianzhang;Hao, Lizhuang;Liu, Shujie;Bao, Yuhong;Liu, Suozhu;Tan, Zhankun

作者机构：

关键词： blood metabolome; metabolic profile; nutrient deficiency; grazing yak

期刊名称：METABOLITES （ 影响因子：5.581； 五年影响因子：5.531 ）

ISSN：

年卷期： 2022 年 12 卷 8 期

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收录情况： SCI

摘要： This study aimed to investigate the changes in the blood metabolic profiles of grazing yaks during the cold season to reveal their physiological status and seek the nutrients needed to be supplemented. Six castrated yaks (3 years old) with 166.8 kg (standard deviation = 5.3) of liveweight grazed in the Qinghai-Tibetan Plateau were used as experimental animals without supplementary feeding. Blood samples of each animal were collected in October and December 2015, and March 2016 for the analysis of serum biochemicals and metabolome. Results showed serum indices involved in protein metabolism in grazing yaks showed greater differences during the cold season than the metabolisms of energy or minerals. Cold stress in December had minor effects on the serum metabolic profiles of yaks compared with those in October. Yaks in October and December shared seven differential serum metabolites and enrichments of the "arachidonic acid metabolism" and "glycine, serine, and threonine metabolism" pathways compared with those in March caused by the shortage of feeds. Summarily, the nutrient deficiency would be influential on the physiological status of grazing yaks during the cold season, especially on the protein metabolism, which could be improved by supplementary feeds.

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