Lignanamides: A comprehensive review of chemical constituents, biological activities, extraction methods and synthetic pathway

文献类型： 外文期刊

第一作者： Sun, Jing

作者： Sun, Jing;Tong, Li-Tao;Chen, Lin-Lin;Xu, Xin;Song, Ya;Yang, Xin-Xin;Guo, Zi-Bin;Mi, Yan;Fan, Bei;Wang, Feng-Zhong;Tu, Peng-Fei;Fan, Bei;Wang, Feng-Zhong;Chen, Lin-Lin;Song, Ya;Zou, Xiang;Sun, Chen-Xin

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关键词： Lignanamides; Chemical constituents; Biological activities; Extraction techniques; Synthetic pathway

期刊名称：FOOD CHEMISTRY （ 影响因子：8.5； 五年影响因子：8.2 ）

ISSN： 0308-8146

年卷期： 2024 年 460 卷

页码：

收录情况： SCI

摘要： Lignanamides are a class of compounds containing amide functional groups in lignans. These compounds have excellent anti-inflammatory and neuroprotective, which have shown great potential in terms of food additives, medicine and health supplement. We summarized the recent progress of lignanamides, including chemical constituents, extraction methods, biological activities, and synthetic pathways. The structures were classified according to an updated nomenclature system, can be classified into sixteen types and have certain roles in many respects such as anti-inflammatory, anti-cancer, and antioxidative, which may be important source of materials for functional food. The potential and limitations of different extraction method, chromatographic packing, and synthetic pathway are analyzed. Notably, this review provides an overview of synthesis pathways and applications of lignanamides, further research is needed to improve extraction efficiency and synthesis method, especially in a greener way for better application.

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