Viscera Characteristics of MSTN-Edited Heterozygous Pigs

文献类型： 外文期刊

第一作者： Pei, Yangli

作者： Pei, Yangli;Song, Yuxin;Chen, Chujie;Feng, Zheng;Li, Hua;Fan, Ziyao;Mu, Yulian;Li, Kui;Fan, Ziyao;Li, Bugao;Li, Kui

作者机构：

关键词： myostatin; pigs; heterozygote; visceral; histomorphology

期刊名称：FRONTIERS IN GENETICS （ 影响因子：4.772； 五年影响因子：4.933 ）

ISSN：

年卷期： 2022 年 13 卷

页码：

收录情况： SCI

摘要： Myostatin (MSTN) is a protein that negatively regulates growth of skeletal muscle, and inactivation of MSTN improves the mass of skeletal muscle. Our previous work found that MSTN+/- pigs have higher muscle depth and lower fat depth compared to wild type without any developmental problems. Therefore, MSTN-edited pigs are most likely to appear as heterozygotes in the potential future market, but the characteristics of organs in digestive and reproductive system of pigs with MSTN gene editing remains unclear. Here, we investigated the histological of the organs in the digestive system and reproductive system in MSTN gene heterozygotes at adult stages. The length of intestine was further compared between adult heterozygous and wild type pigs. We found no significant differences in histomorphology of organs, including heart, duodenum, jejunum, ileum, cecum, colon, testis, epididymis, ovaries, oviducts and uterus, between individuals from two genotypes. Moreover, there was no significant difference in the average length of intestine in adult pigs. Our data provide a reference for further clarifying the applications of MSTN gene edited pigs.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序