文献类型： 外文期刊
第一作者： Ruan, Jue
作者： Ruan, Jue;Ruan, Jue;Li, Heng;Li, Heng;Li, Heng
作者机构：
期刊名称：NATURE METHODS （ 影响因子：28.547； 五年影响因子：44.96 ）
ISSN： 1548-7091
年卷期： 2020 年 17 卷 2 期
页码：
收录情况： SCI
摘要： Wtdbg2 assembles genomes with comparable contiguity and accuracy to existing tools using long-read sequencing data, and is several times faster, especially for large genomes. Existing long-read assemblers require thousands of central processing unit hours to assemble a human genome and are being outpaced by sequencing technologies in terms of both throughput and cost. We developed a long-read assembler wtdbg2 () that is 2-17 times as fast as published tools while achieving comparable contiguity and accuracy. It paves the way for population-scale long-read assembly in future.
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