文献类型： 外文期刊
第一作者： Jiang, Rui
作者： Jiang, Rui;Mu, Yangxiu;Iqbal, Zafar;He, Lili;Zhai, Lijuan;Hou, Jing;Yang, Zhixiang;Tang, Dong;Liu, Xiang;Yang, Minghua;Tang, Dong
作者机构：
关键词： C1 unit; Iron-catalyzed; Ketoxime carboxylates; Polyfunctional pyridines; Nitrones
期刊名称：CHEMISTRYSELECT （ 影响因子：2.109； 五年影响因子：2.054 ）
ISSN： 2365-6549
年卷期： 2020 年 5 卷 15 期
页码：
收录情况： SCI
摘要： Polyfunctional pyridines are backbone of numerous natural products and pharmaceutical reactive intermediates. We have developed an iron-catalyzed cyclization reaction between ketoxime carboxylates and nitrones to afford trisubstituted pyridines. Employing this strategy, we have synthesized a number of trisubstituted pyridines with various functional groups in good yields under simple reaction conditions. It is worth mentioning that the nitrones can serve as a novel C1 unit in organic synthesis.
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