Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat

文献类型： 外文期刊

第一作者： Wang, Hongwei

作者： Wang, Hongwei;Sun, Silong;Ge, Wenyang;Zhao, Lanfei;Hou, Bingqian;Lyu, Zhongfan;Xu, Shoushen;Li, Min;Su, Peisen;Li, Xuefeng;Wang, Guiping;Bo, Cunyao;Fang, Xiaojian;Zhuang, Wenwen;Cheng, Xinxin;Wu, Jianwen;Dong, Luhao;Chen, Wuying;Li, Wen;Xiao, Guilian;Zhao, Jinxiao;Hao, Yongchao;Xu, Ying;Gao, Yu;Liu, Wenjing;Liu, Yanhe;Yin, Huayan;Li, Xiang;Zhao, Yan;Wang, Xiaoqian;Ni, Fei;Ma, Xin;Li, Anfei;Kong, Lingrang;Wang, Kai;Chen, Liyang;Guo, Jun;Li, Jiazhu;Xu, Steven S.;Bai, Guihua;Nevo, Eviatar;Gao, Caixia;Ohm, Herbert

作者机构：

期刊名称：SCIENCE （ 影响因子：47.728； 五年影响因子：51.433 ）

ISSN： 0036-8075

年卷期： 2020 年 368 卷 6493 期

页码：

收录情况： SCI

摘要： Fusarium head blight (FHB), a fungal disease caused by Fusarium species that produce food toxins, currently devastates wheat production worldwide, yet few resistance resources have been discovered in wheat germplasm. Here, we cloned the FHB resistance gene Fhb7 by assembling the genome of Thinopyrum elongatum, a species used in wheat distant hybridization breeding. Fhb7 encodes a glutathione S-transferase (GST) and confers broad resistance to Fusarium species by detoxifying trichothecenes through de-epoxidation. Fhb7 GST homologs are absent in plants, and our evidence supports that Th. elongatum has gained Fhb7 through horizontal gene transfer (HGT) from an endophytic Epichloe species. Fhb7 introgressions in wheat confers resistance to both FHB and crown rot in diverse wheat backgrounds without yield penalty, providing a solution for Fusarium resistance breeding.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序