文献类型： 外文期刊
第一作者： Yu, Xinyu
作者： Yu, Xinyu;Xu, Qilan;Chen, Jin;Wu, Yuan;Jiang, Huijun;Wei, Wei;Zulipikaer, Azhati;Guo, Yan;Jirimutu;Chen, Jin;Chen, Jin
作者机构：
期刊名称：BIOMATERIALS SCIENCE （ 影响因子：6.843； 五年影响因子：6.747 ）
ISSN： 2047-4830
年卷期： 2020 年 8 卷 13 期
页码：
收录情况： SCI
摘要： Nanobodies are antigen binding variable domains of heavy-chain antibodies without light-chains, and these biomolecules occur naturally in the serum of Camelidae species. Nanobodies have a compact structure and low molecular weight when compared with antibodies, and are the smallest active antigenbinding fragments. Because of their remarkable stability and manipulable characteristics, nanobodies have been incorporated into biomaterials and used as molecular recognition and tracing agents, drug delivery systems, molecular imaging tools and disease therapeutics. This review summarizes recent progress in this field focusing on nanobodies as versatile biomolecules for biomedical applications.
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