Effects of long-term feeding diets supplemented with Lactobacillus reuteri 1 on growth performance, digestive and absorptive function of the small intestine in pigs

文献类型： 外文期刊

第一作者： Tian, Zhimei

作者： Tian, Zhimei;Cui, Yiyan;Lu, Huijie;Ma, Xianyong

作者机构：

关键词： Lactobacillus reuteri 1; Growth performance; Intestinal digestion and absorption; Pigs

期刊名称：JOURNAL OF FUNCTIONAL FOODS （ 影响因子：4.451； 五年影响因子：4.907 ）

ISSN： 1756-4646

年卷期： 2020 年 71 卷

页码：

收录情况： SCI

摘要： This study aimed to investigate the effects of long-term feeding diets supplemented with antibiotics and Lactobacillus reuteri 1 (LR1) on growth performance, intestinal digestion and absorption in pigs. The results showed that both LR1 and the antibiotics increased body weight of the piglets after 42-d (P < 0.05), and showed a tendency to promote growth performance in growing-finishing pigs. LR1 significantly improved jejunal and ileal mucosal morphology and increased expression of jejunal glucosidase and ileal cholecystokinin, digestive enzymes and nutrient transporters. The antibiotics decreased jejunal lactase, BO + AT1, FATP1, GLUT2, ileal y + LAT1, and GLUT2 (P < 0.05). LR1 stimulated protein synthesis of ileal mucosa rather than jejunal mucosa compared to control and antibiotic groups (P < 0.05). In conclusion, LR1 could be an alternative to antibiotics as a growth promoter that improves mucosal morphology, synthesis and secretion of cholecystokinin and digestion and absorption of small intestine.

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