文献类型： 外文期刊
第一作者： Ye, Dandan
作者： Ye, Dandan;Ji, Zhaoyang;Shi, Hongyan;Chen, Jianfei;Shi, Da;Cao, Liyan;Liu, Jianbo;Li, Mingwei;Dong, Hui;Jing, Zhaoyang;Wang, Xiaobo;Liu, Qiuge;Fan, Qianjin;Cong, Guangyi;Zhang, Jiyu;Han, Yuru;Zhang, Xin;Feng, Li;Zhou, Jiyong;Gu, Jinyan
作者机构：
期刊名称：ARCHIVES OF VIROLOGY （ 影响因子：2.574； 五年影响因子：2.466 ）
ISSN： 0304-8608
年卷期： 2020 年 165 卷 10 期
页码：
收录情况： SCI
摘要： Mammalian orthoreoviruses (MRVs) infect almost all mammals, and there are some reports on MRVs in China. In this study, a novel strain was identified, which was designated as HLJYC2017. The results of genetic analysis showed that MRV HLJYC2017 is a reassortant strain. According to biological information analysis, different serotypes of MRV contain specific amino acid insertions and deletions in the sigma 1 protein. Neutralizing antibody epitope analysis revealed partial cross-protection among MRV1, MRV2, and MRV3 isolates from China. L3 gene recombination in MRV was identified for the first time in this study. The results of this study provide valuable information on MRV reassortment and evolution.
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