A Systematic Review on Secondary Metabolites of Paecilomyces Species: Chemical Diversity and Biological Activity

文献类型: 外文期刊

第一作者: Li, Xiu-Qi

作者: Li, Xiu-Qi;Xu, Kuo;Liu, Xin-Min;Zhang, Peng;Li, Xiu-Qi

作者机构:

关键词: Paecilomyces; secondary metabolites; chemical diversity; biological activity

期刊名称:PLANTA MEDICA ( 影响因子:3.352; 五年影响因子:3.4 )

ISSN: 0032-0943

年卷期: 2020 年 86 卷 12 期

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收录情况: SCI

摘要: Fungi are well known for their ability to synthesize secondary metabolites, which have proven to be a rich resource for exploring lead compounds with medicinal and/or agricultural importance. The genera Aspergillus, Penicillium, and Talaromyces are the most widely studied fungal groups, from which a plethora of bioactive metabolites have been characterized. However, relatively little attention has been paid to the genus Paecilomyces, which has been reported to possess great potential for its application as a biocontrol agent. Meanwhile, a wide structural array of metabolites with attractive bioactivities has been reported from this genus. This review attempts to provide a comprehensive overview of Paecilomyces species, with emphasis on the chemical diversity and relevant biological activities of these metabolic products. Herein, a total of 148 compounds and 80 references are cited in this review, which is expected to be beneficial for the development of medicines and agrochemicals in the near future.

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